Objective Dysregulation of autonomic nervous system and hypothalamic-pituitary-adrenal
(HPA) axis function is a putative intermediate phenotype linking childhood adversity (CA) …

Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes …

Abstract [Correction Notice: An Erratum for this article was reported in Vol 129 (4) of Journal
of Abnormal Psychology (see record 2020-27239-001). In the article, the indirect effects in …

Childhood adversity is associated with poor mental and physical health outcomes across the
life span. Alterations in the hypothalamic–pituitary–adrenal axis are considered a key …

Background Research on early adversity, stress biology, and child development has grown
exponentially in recent years. Findings We review the current evidence for the hypothalamic …

Recent neurodevelopmental and evolutionary theories offer strong theoretical rationales
and some empirical evidence to support the importance of specific dimensions of early …

Objective Disruptions in stress response system development have been posited as
mechanisms linking child maltreatment (CM) to psychopathology. Existing theories predict …

Exposure to childhood adversity is common and a powerful risk factor for many forms of
psychopathology. In this opinion piece, we argue for greater translation of knowledge about …

Research on childhood adversity has traditionally focused on single types of adversity,
which is limited because of high co-occurrence, or on the total number of adverse …

Exposure to adversity in childhood is associated with elevations in numerous physical and
mental health outcomes across the life course. The biological embedding of early …