Systems biology is an integrative discipline connecting the molecular components within a
single biological scale and also among different scales (eg cells, tissues and organ systems) …

High‐throughput experimental techniques for generating genomes, transcriptomes,
proteomes, metabolomes, and interactomes have provided unprecedented opportunities to …

This comprehensively revised second edition of Computational Systems Biology discusses
the experimental and theoretical foundations of the function of biological systems at the …

For life to be understood and disease to become manageable, the wealth of postgenomic
data now needs to be made dynamic. This development requires systems biology …

Understanding complex biological systems requires extensive support from software tools.
Such tools are needed at each step of a systems biology computational workflow, which …

In systems biology, biologically relevant quantitative modelling of physiological processes
requires the integration of experimental data from diverse sources. Recent developments in …

Systems biology is a comprehensive quantitative analysis of the manner in which all the
components of a biological system interact functionally over time. Such an analysis is …

Systems biology is in an exponential development stage in recent years and has been
widely utilized in biomedicine to better understand the molecular basis of human disease …

Mathematical biology and pharmacology models have a long and rich history in the fields of
medicine and physiology, impacting our understanding of disease mechanisms and the …

With the ever-increasing flow of high-throughput gene expression, protein interaction and
genome sequence data, researchers gradually approach a system-level understanding of …