Quality-of-Life Improvement with Relugolix Combination Therapy in Patients with Heavy Menstrual Bleeding Associated with Uterine Fibroids: Results from the Liberty …

A Al-Hendy, EA Stewart, R Venturella, A Poindexter… - Fertility and …, 2020 - fertstert.org
Objective To evaluate the effect of Relugolix combination therapy (Rel-CT) on Quality of Life
(QoL) using the Uterine Fibroid Symptom Health-Related QoL (UFS-QoL) questionnaire, an …

LIBERTY randomized withdrawal study: 2-year efficacy and safety of relugolix combination therapy in women with heavy menstrual bleeding associated with uterine …

A Al-Hendy, R Venturella, JCA Ferreira, Y Li… - Fertility and …, 2021 - fertstert.org
Objective In the pivotal LIBERTY 1 and 2 trials and Long-Term Extension (LTE) study, once-
daily relugolix combination therapy (Rel-CT: relugolix 40 mg, estradiol 1 mg, norethindrone …

O-136 Once-daily relugolix combination therapy results in sustained reduction in symptoms and improved quality of life in women with uterine fibroids treated over 52 …

A Lukes, R Venturella, A Al-Hendy… - Human …, 2021 - academic.oup.com
Study question What is the effect of relugolix combination therapy (Relugolix-CT) on
symptom burden and health-related quality-of-life (HR-QoL) in patients with uterine fibroids …

Relugolix combination therapy significantly reduced menstrual blood loss with first treatment cycle in women with heavy menstrual bleeding associated with uterine …

R Venturella, A Al-Hendy, AS Lukes, J Kang… - Fertility and …, 2020 - fertstert.org
Objective To evaluate the time to treatment response with once-daily Relugolix combination
therapy (Rel-CT), assessed by decrease in menstrual blood loss (MBL) volume observed in …

[HTML][HTML] Quality of life with relugolix combination therapy for uterine fibroids: LIBERTY randomized trials

EA Stewart, AS Lukes, R Venturella, Y Li… - American journal of …, 2023 - Elsevier
Background Symptomatic uterine fibroids are burdensome to live with; they are associated
with symptom-related distress, affect daily activities, and reduce health-related quality of life …

Measuring patient-reported outcomes in women with heavy menstrual bleeding associated with uterine fibroids: the bleeding and pelvic discomfort scale

J Li, JB Kang, E Hunsche, S Hudgens - Fertility and Sterility, 2019 - fertstert.org
Objective The Uterine Fibroid Symptom and Quality of Life (UFS-QoL) instrument consists of
6 scales and has been used frequently in clinical trials; the symptom severity scale has 8 …

[引用][C] Elagolix improves quality of life in women with heavy menstrual bleeding associated with uterine fibroids: evidence from a phase 2b randomized trial

M Diamond, AM Soliman, J Gao, C Owens… - Fertility and …, 2017 - fertstert.org
Objective To evaluate the impact of elagolix, an oral gonadotropin-releasing hormone
antagonist, on the health-related quality of life (HRQL) in women with heavy menstrual …

Quality of life improvements in women with uterine fibroids treated with relugolix combination therapy during the LIBERTY long‐term extension study: a descriptive …

R Venturella, AS Lukes, R Wu… - … of Gynecology & …, 2024 - Wiley Online Library
Objective To investigate the effects of 52 weeks of treatment with relugolix combination
therapy (relugolix 40 mg, estradiol 1 mg, norethindrone acetate 0.5 mg) on symptoms of …

[HTML][HTML] LIBERTY randomized withdrawal study: relugolix combination therapy for heavy menstrual bleeding associated with uterine fibroids

A Al-Hendy, R Venturella, JCA Ferreira, Y Li… - American Journal of …, 2023 - Elsevier
Background In the pivotal LIBERTY 1 and 2 trials and long-term extension study, once-daily
relugolix combination therapy (40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone …

O-135 Long term secondary efficacy of linzagolix for heavy menstrual bleeding (HMB) due to uterine fibroids (UF): 52-week results from two placebo-controlled …

H Taylor, J Donnez, F Petraglia… - Human …, 2021 - academic.oup.com
Study question Are symptomatic improvements in women with UF observed after 24 weeks
of linzagolix treatment with or without add-back therapy (ABT) maintained over 52 weeks …