Asna et al.(2003) reported that decreased susceptibility to ciprofloxacin among strains of S.
Typhi could not be detected by the disc diffusion method; their isolates were fully susceptible …

The incidence of nalidixic acid-resistant Salmonella typhi (NARST) with decreased
susceptibility to ciprofloxacin was investigated in an urban referral hospital in Dhaka …

Background: Fluoroquinolones are the drugs of choice for the treatment of typhoid fever. But
the recent increase in minimum inhibitory concentration (MIC) values of ciprofloxacin in …

Typhoid fever is endemic in Bangladesh (1). Until the mid-1980s, ampicillin,
chloramphenicol, or co-trimoxazole was the standard treatment for typhoid fever. Since then …

Typhoid fever due to multidrug-resistant Salmonella enterica serovar Typhi is a global public
health problem, with an estimated 30 million cases and 600,000 deaths annually (7). Since …

BACKGROUND & OBJECTIVES: Clinical non response to ciprofloxacin therapy in enteric
fever is increasingly being encountered in endemic areas possibly due to the increase in the …

Ciprofloxacin has become the antibiotic of choice for the treatment of typhoid fever with the
emergence and worldwide spread of Salmonella enterica typhi strains resistant to …

A total of 1,059 Salmonella enterica serovar Typhi were isolated from blood samples during
January 2006 to October 2007 from urban rural facilities in Dhaka, Bangladesh, of which …

Blood samples were inoculated into brain heart infusion broth and incubated at 37 C.
Subcultures were made onto MacConkey agar and Hektoen Enteric Agar plates (Hi-Media …

Renuka et al.(2004) the MIC values. It has been shown in studies involving well-
characterized single-step mutants that each mutation affecting quinolone-resistance reduces …