Coronary microvascular dysfunction in diabetes mellitus

A Kibel, K Selthofer-Relatic… - Journal of …, 2017 - journals.sagepub.com
The significance, mechanisms and consequences of coronary microvascular dysfunction
associated with diabetes mellitus are topics into which we have insufficient insight at this …

[HTML][HTML] Coronary microvascular dysfunction in diabetes mellitus: a review

A Picchi, S Capobianco, T Qiu, M Focardi… - World journal of …, 2010 - ncbi.nlm.nih.gov
The exploration of coronary microcirculatory dysfunction in diabetes has accelerated in
recent years. Cardiac function is compromised in diabetes. Diabetic patients manifest …

Microvascular perfusion and transport in the diabetic heart

PF McDONAGH, JY Hokama - Microcirculation, 2000 - Taylor & Francis
Diabetes is a chronic disease of metabolic dysfunction that is increasing worldwide. The
hyperglycemia associated with diabetes causes significant protein alterations and an …

Coronary microvascular dysfunction in diabetes mellitus: pathogenetic mechanisms and potential therapeutic options

T Salvatore, R Galiero, A Caturano, E Vetrano… - Biomedicines, 2022 - mdpi.com
Diabetic patients are frequently affected by coronary microvascular dysfunction (CMD), a
condition consisting of a combination of altered vasomotion and long-term structural change …

Bimodal pattern of coronary microvascular involvement in diabetes mellitus

M Sezer, M Kocaaga, E Aslanger, A Atici… - Journal of the …, 2016 - Am Heart Assoc
Background The contribution of functionally disturbed coronary autoregulation and
structurally impaired microvascular vasodilatory function to reduced coronary flow velocity …

Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes

MF Di Carli, J Janisse, J Ager, G Grunberger - Journal of the American …, 2003 - jacc.org
Objectives: We sought to determine the differences in coronary microvascular function
between patients with type 1 (insulin-deficient) and type 2 (insulin-resistant) diabetes …

Role of microangiopathy in diabetic cardiomyopathy

A Adameova, NS Dhalla - Heart failure reviews, 2014 - Springer
Although heart disease due to diabetes is mainly associated with complications of the large
vessels, microvascular abnormalities are also considered to be involved in altering cardiac …

Novel mechanisms of endothelial dysfunction in diabetes

G Yang, R Lucas, R Caldwell, L Yao… - Journal of …, 2010 - Elsevier
Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This
condition increases the risk of developing coronary, cerebrovascular, and peripheral arterial …

Coronary microvascular disease as an early culprit in the pathophysiology of diabetes and metabolic syndrome

H Labazi, AJ Trask - Pharmacological research, 2017 - Elsevier
Metabolic syndrome (MetS) is a group of cardio-metabolic risk factors that includes obesity,
insulin resistance, hypertension, and dyslipidemia; these are also a combination of …

The pathogenic role of coronary microvascular dysfunction in the setting of other cardiac or systemic conditions

RE Konst, TJ Guzik, JC Kaski… - Cardiovascular …, 2020 - academic.oup.com
Coronary microvascular dysfunction (CMD) plays a pathogenic role in cardiac and systemic
conditions other than microvascular angina. In this review, we provide an overview of the …