Lung cancer is a major cause of cancer-related death in the developed countries and the
overall survival rate has still an extremely poor. Cigarette smoking is an established risk …

Lung cancer results from man-made and natural environmental exposures acting in concert
with both genetic and acquired characteristics. Chronic inhalation of cigarette smoke is a …

Susceptibility to lung cancer has been shown to be modulated by host specific factors.
Inheritance of different polymorphic cytochrome P450s (CYPs) and the glutathione S …

Available data indicate that there are significant differences in individual susceptibility to
lung cancer within the human population. It is believed to be underlie by inherited genetic …

Activity of some enzymes implicated in the metabolism of tobacco carcinogens presents a
great variability between individuals due to the existence of a polymorphism in gene coding …

Lung cancer is the leading cause of cancer death worldwide, and cigarette smoking is the
major environmental factor for its development. To elucidate the genetic differences in the …

Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …

The major risk factor for lung cancer is exposure to tobacco smoke. Exposure to radon,
heavy metals used in smelting, and asbestos also greatly increase risks for lung cancer …

Lung cancer occurs through a complex multistage process that results from the combination
of carcinogen exposure and genetic susceptibilities. The primary etiology of lung cancer is …

Background Epidemiological and family studies suggest that lung cancer results from the
combined effects of age, smoking and genetic factors. Chronic obstructive pulmonary …