Apelin is a biologically active protein encoded by the APLN gene. It was first isolated in 1998
as a ligand for the APJ receptor. It exists in several isoforms differing in polypeptide chain …

Apelin is a recently discovered biologically active peptide present in several isoforms that
are agonists for orphan receptor APJ. Apelin and APJ receptor were found in the central …

The purpose of this study was to investigate apelin activity in patients with essential
hypertension (EH) according to age and gender. Examination of 94 patients with EH was …

Apelin is a new cytokine with proven functions in the cardiovascular system. It is derived
from a single gene and has several isoforms that differ in polypeptide chain length and …

Apelin is an endogenous peptide acting on the APJ receptor. It consists of several isoforms
characterized by different numbers of amino acids. The number of amino acids in the active …

Background: The peptide apelin has antihypertensive and antidiabetic properties, but its role
in the processes of cardiac remodeling in patients with hypertension and type 2 diabetes …

Apelin is a novel peptide that acts through the APJ receptor, sharing similarities with the
angiotensin II–angiotensin II type 1 receptor pathway. It is a peripheral vasodilator, powerful …

The purpose of the current study was to determine effects of apelin on the cardiovascular
system in the light of the literature. Adipose tissue, which is considered as the body's energy …

Objective Apelin is a novel peptide of a wide expression in the human body and with
multiple biological functions. It was first isolated and described in 1998 by Tatemoto et al. It …

Apelin is a G protein-linked receptor endogenous ligand, synthesized as a 77-amino acid
pre-propeptide. Increased expression of apelin is present in many cardiovascular (CV) …