Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies

B Selvarajah, M Platé, RC Chambers - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis is the concluding pathological outcome and major cause of morbidity and mortality
in a number of common chronic inflammatory, immune-mediated and metabolic diseases …

Progress in understanding and treating idiopathic pulmonary fibrosis: Recent insights and emerging therapies

H Guo, J Sun, S Zhang, Y Nie, S Zhou… - Frontiers in …, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

New therapeutics based on emerging concepts in pulmonary fibrosis

V Sontake, PR Gajjala, RK Kasam… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Fibrosis is an irreversible pathological endpoint in many chronic diseases,
including pulmonary fibrosis. Idiopathic pulmonary fibrosis (IPF) is a progressive and often …

Idiopathic pulmonary fibrosis: an update on pathogenesis

Q Mei, Z Liu, H Zuo, Z Yang, J Qu - Frontiers in pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

Emerging therapeutic interventions for idiopathic pulmonary fibrosis

S Chakraborty, P Chopra, SV Ambi… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Idiopathic pulmonary fibrosis (IPF) is a devastating and relentlessly progressive
lung disorder. Previously, it was thought to be a chronic inflammatory disease; however, it is …

Idiopathic pulmonary fibrosis: pathobiology of novel approaches to treatment

TM Maher - Clinics in chest medicine, 2012 - chestmed.theclinics.com
Idiopathic pulmonary fibrosis is a nonmalignant disease, yet it carries a prognosis akin to, or
even worse than, many cancers. Until recently, lung transplantation has been the only …

Beyond the diagnosis of idiopathic pulmonary fibrosis; the growing role of systems biology and stratified medicine

TM Maher - Current Opinion in Pulmonary Medicine, 2013 - journals.lww.com
Use of molecular research techniques in large populations of well-phenotyped patients is
leading to major advances in understanding of IPF. As new treatments for IPF emerge, it is to …

Idiopathic pulmonary fibrosis: an update

P Spagnolo, N Sverzellati, G Rossi, A Cavazza… - Annals of …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic
interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults …

Pulmonary fibrosis: from pathogenesis to clinical decision-making

T Koudstaal, M Funke-Chambour, M Kreuter… - Trends in molecular …, 2023 - cell.com
Pulmonary fibrosis (PF) encompasses a spectrum of chronic lung diseases that
progressively impact the interstitium, resulting in compromised gas exchange …

Progress in understanding and treating idiopathic pulmonary fibrosis

JA Kropski, TS Blackwell - Annual review of medicine, 2019 - annualreviews.org
This is a time of substantial progress in the evaluation and care of patients with idiopathic
pulmonary fibrosis (IPF). In addition to the approval and widespread availability of the first …