Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm
syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy …

Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Objectives To develop predictive criteria for COVID-19-associated cytokine storm (CS), a
severe hyperimmune response that results in organ damage in some patients infected with …

Objective Infection with the novel coronavirus SARS–CoV‐2 triggers severe illness with high
mortality in a subgroup of patients. Such a critical course of COVID‐19 is thought to be …

Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

Highlights•Clinical picture generally manifests as “overlap syndrome” and leads to vicious
circle.•Early identification of rising cytokine storm and multilevel course of treatment is …

Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …