[PDF][PDF] ACE2 can be a target for therapeutic purpose of COVID-19

M Khan, Z Cao, A Khan - Authorea Preprints, 2020 - techrxiv.org
Letter to editor It has been demonstrated that the latest outbreak-causing novel coronavirus
pneumonia (COVID-19) virus (2019-nCoV, SARS-CoV-2) invades human alveolar epithelial …

ACE2 and COVID-19 and the resulting ARDS

X Zhang, S Li, S Niu - Postgraduate medical journal, 2020 - academic.oup.com
This article reviews the correlation between ACE2 and COVID-19 and the resulting acute
respiratory distress syndrome (ARDS). ACE2 is a crucial component of the renin-angiotensin …

The regulation of ACE-2 in the heart and lungs

J Kopel, T Tenner, G Brower… - … Respiratory and Critical …, 2021 - pulmonarychronicles.com
The pathogenesis of SARS-CoV-2 infection or COVID-19 disease remains an active and
rapidly evolving area of investigation. Currently, the angiotensin-converting enzyme 2 …

Searching therapeutic strategies of COVID-19 from Angiotensin-converting Enzyme 2: The receptor of 2019-nCoV and SARS-CoV

Z TANG, S LI, W XU, Z SHEN - Chinese General Practice, 2020 - chinagp.net
The COVID-19 outbreak occurred in Wuhan, China, in December 2019 has aroused wide
public concern. Both 2019-nCoV and SARS-CoV belong to the coronaviridae family, and …

COVID-19: is the ACE2 just a foe?

H Jakovac - American Journal of Physiology-Lung Cellular …, 2020 - journals.physiology.org
TO THE EDITOR: I read with great interest and pleasure the recent Letter “Covid-19 infection
and mortality: a physiologist's perspective enlightening clinical features and plausible …

Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

Y Li, W Zhou, L Yang, R You - Pharmacological research, 2020 - Elsevier
The renin-angiotensin system (RAS) is crucial for the physiology and pathology of all the
organs. Angiotensin-converting enzyme 2 (ACE2) maintains the homeostasis of RAS as a …

Lisinopril increases lung ACE2 levels and SARS-CoV-2 viral load and decreases inflammation but not disease severity in experimental COVID-19

Y Da Silva Santos, RL Pagni, TH Gamon… - Frontiers in … - frontiersin.org
COVID-19 causes more severe and frequently fatal disease in patients with pre-existing
comorbidities such as hypertension and heart disease. SARS-CoV-2 virus enters host cells …

[HTML][HTML] ACE2 in SARS-CoV-2-Mediated COVID-19: A Brief Review

PS Kozani, SD Shokoohi, N Baharifar… - Trends in Medical …, 2022 - brieflands.com
: Angiotensin-converting enzyme 2 (ACE2) is widely known as the essential receptor for
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is the cause …

Spike-mediated ACE2 down-regulation was involved in the pathogenesis of SARS-CoV-2 infection

X Gao, S Zhang, J Gou, Y Wen, L Fan, J Zhou, G Zhou… - Journal of Infection, 2022 - Elsevier
The ongoing global pandemic of Coronavirus disease 2019 (COVID-19) poses a serious
threat to human health, with patients reportedly suffering from thrombus, vascular injury and …

Don't judge too RAShly: The multifaceted role of the renin-angiotensin system and its therapeutic potential in COVID-19

T Walther, WM Kuebler - American Journal of Physiology …, 2020 - journals.physiology.org
TO THE EDITOR: We read with great interest the recent Letter by Abassi and colleagues (1)
highlighting—among others—the emerging role of the renin-angiotensin system (RAS) as …