Intestinal bacteria and ageing

EJ Woodmansey - Journal of applied microbiology, 2007 - academic.oup.com
Advancements in science and medicine, as well as improved living standards, have led to a
steady increase in life expectancy, and subsequently a rise in the elderly population. The …

The role of the microbiome in gastrointestinal inflammation

DJ Sanders, S Inniss, G Sebepos-Rogers… - Bioscience …, 2021 - portlandpress.com
The microbiome plays an important role in maintaining human health. Despite multiple
factors being attributed to the shaping of the human microbiome, extrinsic factors such diet …

[HTML][HTML] Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality

RI Clark, A Salazar, R Yamada, S Fitz-Gibbon… - Cell reports, 2015 - cell.com
Alterations in the composition of the intestinal microbiota have been correlated with aging
and measures of frailty in the elderly. However, the relationships between microbial …

The gut microbiota is an emerging target for improving brain health during ageing

M Boehme, KE Guzzetta, C Wasén, LM Cox - Gut microbiome, 2023 - cambridge.org
The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host
throughout lifespan, including through its ability to impact brain function and regulate …

The landscape in the gut microbiome of long-lived families reveals new insights on longevity and aging–relevant neural and immune function

J Wang, J Qie, D Zhu, X Zhang, Q Zhang, Y Xu… - Gut …, 2022 - Taylor & Francis
Human longevity has a strong familial and genetic component. Dynamic characteristics of
the gut microbiome during aging associated with longevity, neural, and immune function …

Is inflammageing influenced by the microbiota in the aged gut? A systematic review

CM Shintouo, T Mets, D Beckwee, I Bautmans… - Experimental …, 2020 - Elsevier
Ageing is characterized by a low-grade chronic inflammation marked by elevated circulating
levels of inflammatory mediators. This chronic inflammation occurring in the absence of …

Microbiome: effects of ageing and diet

N Salazar, S González, AM Nogacka… - Current issues in …, 2020 - mdpi.com
The microbial community inhabiting our intestine, known as' microbiota', and the ensemble
of their genomes (microbiome) regulate important functions of the host, being essential for …

[HTML][HTML] Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity

TTT Tran, FJ Cousin, DB Lynch, R Menon, J Brulc… - Microbiome, 2019 - Springer
Background There are complex interactions between aging, frailty, diet, and the gut
microbiota; modulation of the gut microbiota by diet could lead to healthier aging. The …

Microbes in gastrointestinal health and disease

AS Neish - Gastroenterology, 2009 - Elsevier
Most, if not all, animals coexist with a complement of prokaryotic symbionts that confer a
variety of physiologic benefits. In humans, the interaction between animal and bacterial cells …

[HTML][HTML] Adjusting for age improves identification of gut microbiome alterations in multiple diseases

TS Ghosh, M Das, IB Jeffery, PW O'Toole - elife, 2020 - elifesciences.org
Interaction between disease-microbiome associations and ageing has not been explored in
detail. Here, using age/region-matched sub-sets, we analysed the gut microbiome …