This article provides an overview of the development, structure and activity of various metal complexes with anti-cancer activity. Chemical researchers continue to work on the …
Research into cancer therapeutics has uncovered various potential medications based on metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
For the past 41 years, metal-based drugs have been widely used for the treatment of cancer. Cisplatin and follow-up drugs carboplatin (Paraplatin™) and oxaliplatin (Eloxatin™) have …
Numerous biologically active metal complexes are reported for their unique features and enhanced functions, particularly towards the inhibition of cancer progression. With the …
Metal-based complexes have demonstrated significant anticancer effects and have emerged as candidates with great potential for cancer therapy. These agents are effective in a variety …
The design of novel anticancer agents is one of the most active fields in Medicinal Chemistry, as the number of effective drugs for treatment of cancer is still very limited. This …
P Nath, A Datta, T Sen, S Adhikari - … in Cancer Detection and Monitoring of …, 2024 - Elsevier
Since the discovery of cisplatin's antitumor efficacy, researchers have concentrated their efforts on developing novel metal-based anticancer drugs that might be employed in cancer …
C Riccardi, M Piccolo - International Journal of Molecular Sciences, 2023 - mdpi.com
Indeed, metal-containing complexes are endowed with impressive chemical diversity and versatility, depending on the metal of choice, its oxidation state, the number and type of …
Y Bai, G Aodeng, L Ga, W Hai, J Ai - Pharmaceutics, 2023 - mdpi.com
Cancer treatments, including traditional chemotherapy, have failed to cure human malignancies. The main reasons for the failure of these treatments are the inevitable drug …