[HTML][HTML] Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CM Curieses Andrés, JM Pérez de Lastra… - 2024 - digital.csic.es
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

[HTML][HTML] Unconventional anticancer metallodrugs and strategies to improve their pharmacological profile

M Contel - Inorganics, 2019 - mdpi.com
For the past 41 years, metal-based drugs have been widely used for the treatment of cancer.
Cisplatin and follow-up drugs carboplatin (Paraplatin™) and oxaliplatin (Eloxatin™) have …

Recent developments on other platinum metal complexes as target-specific anticancer therapeutics

TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Design, synthesis, characterization and biological studies of ruthenium and gold compounds with anticancer properties

A Garza-Ortiz - 2008 - scholarlypublications …
The design of novel anticancer agents is one of the most active fields in Medicinal
Chemistry, as the number of effective drugs for treatment of cancer is still very limited. This …

Emergence of metal-based anticancer therapeutics: A promising perspective

P Nath, A Datta, T Sen, S Adhikari - … in Cancer Detection and Monitoring of …, 2024 - Elsevier
Since the discovery of cisplatin's antitumor efficacy, researchers have concentrated their
efforts on developing novel metal-based anticancer drugs that might be employed in cancer …

[HTML][HTML] Metal-based complexes in cancer

C Riccardi, M Piccolo - International Journal of Molecular Sciences, 2023 - mdpi.com
Indeed, metal-containing complexes are endowed with impressive chemical diversity and
versatility, depending on the metal of choice, its oxidation state, the number and type of …

[HTML][HTML] Research Progress of Metal Anticancer Drugs

Y Bai, G Aodeng, L Ga, W Hai, J Ai - Pharmaceutics, 2023 - mdpi.com
Cancer treatments, including traditional chemotherapy, have failed to cure human
malignancies. The main reasons for the failure of these treatments are the inevitable drug …