Mammary gland development

H Macias, L Hinck - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

[HTML][HTML] The molecular basis of mammary gland development and epithelial differentiation

PF Slepicka, AVH Somasundara… - Seminars in cell & …, 2021 - Elsevier
Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Embryonic mammary gland development

E Spina, P Cowin - Seminars in cell & developmental biology, 2021 - Elsevier
Embryonic mammary gland development involves the formation of mammary placodes,
invagination of flask-shaped mammary buds and development of miniature bi-layered ductal …

Mammary gland development: cell fate specification, stem cells and the microenvironment

JL Inman, C Robertson, JD Mott, MJ Bissell - Development, 2015 - journals.biologists.com
The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

Signalling pathways implicated in early mammary gland morphogenesis and breast cancer

B Howard, A Ashworth - PLoS genetics, 2006 - journals.plos.org
Specification of mammary epithelial cell fate occurs during embryogenesis as cells
aggregate to form the mammary anlage. Within the embryonic mammary bud, a population …

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

CJ Watson, WT Khaled - 2008 - journals.biologists.com
Mammary gland development occurs through distinctive stages throughout embryonic and
pubertal development and reproductive life. At each stage, different signals are required to …

Hormonal and local control of mammary branching morphogenesis

MD Sternlicht, H Kouros‐Mehr, P Lu, Z Werb - Differentiation, 2006 - Wiley Online Library
Unlike other branched organs, the mammary gland undergoes most of its branching during
adolescent rather than embryonic development. Its morphogenesis begins in utero, pauses …

Molecular mechanisms guiding embryonic mammary gland development

P Cowin, J Wysolmerski - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The mammary gland is an epidermal appendage that begins to form during embryogenesis,
but whose development is only completed during pregnancy. Each mammary gland begins …

The mammary gland: basic structure and molecular signaling during development

SK Biswas, S Banerjee, GW Baker, CY Kuo… - International Journal of …, 2022 - mdpi.com
The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

Establishing a framework for the functional mammary gland: from endocrinology to morphology

RC Hovey, JF Trott, BK Vonderhaar - Journal of mammary gland biology …, 2002 - Springer
From its embryonic origins, the mammary gland in females undergoes a course of ductal
development that supports the establishment of alveolar structures during pregnancy prior to …