Background Heterotopic ossification (HO), either acquired (aHO) or hereditary, such as
fibrodysplasia ossificans progressiva (FOP), is a serious condition without effective …

Put most simply, heterotopic ossification (HO) is the abnormal formation of bone at
extraskeletal sites. HO can be classified into two main subtypes, genetic and acquired …

Heterotopic ossification (HO), the abnormal formation of true marrow-containing bone within
extraskeletal soft tissues, is a serious bony disorder that may be either acquired or …

Bone marrow contains a non-hematopoietic, clonogenic, multipotent population of stromal
cells that are later called mesenchymal stem cells (MSC). Similar cells that share many …

Background: Individuals who have fibrodysplasia ossificans progressiva develop an ectopic
skeleton because of genetic dysregulation of bone morphogenetic protein (BMP) signaling …

Heterotopic ossification (HO), or the abnormal development of bone tissue in soft-tissue
locations, can be physically debilitating and clinically devastating. For unclear reasons, HO …

Heterotopic ossification (HO), characterized by the formation of mature bone in the soft
tissues, is a complication that can accompany musculoskeletal injury, and it is a frequent …

Heterotopic ossification (HO), the formation of extra-skeletal bone in soft tissues, is a
pathologic process occurring after substantial burns or trauma, or in patients with type I bone …

Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by
extraskeletal bone formation after injury. The exact pathogenesis of HO remains unknown …

Heterotopic ossification (HO) is a debilitating pathology where ectopic bone develops in
areas of soft tissue. HO can develop as a consequence of traumatic insult or as a result of …