Mammary gland development: cell fate specification, stem cells and the microenvironment

JL Inman, C Robertson, JD Mott, MJ Bissell - Development, 2015 - journals.biologists.com
The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

CJ Watson, WT Khaled - 2008 - journals.biologists.com
Mammary gland development occurs through distinctive stages throughout embryonic and
pubertal development and reproductive life. At each stage, different signals are required to …

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective

C Brisken, S Duss - Stem cell reviews, 2007 - Springer
The mammary gland is a unique organ in that it undergoes most of its development after
birth under the control of systemic hormones. Whereas in most other organs stem cells …

Mammary gland development

H Macias, L Hinck - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

[HTML][HTML] Stem cells and the differentiation hierarchy in mammary gland development

NY Fu, E Nolan, GJ Lindeman… - Physiological …, 2020 - journals.physiology.org
The mammary gland is a highly dynamic organ that undergoes profound changes within its
epithelium during puberty and the reproductive cycle. These changes are fueled by …

[HTML][HTML] The molecular basis of mammary gland development and epithelial differentiation

PF Slepicka, AVH Somasundara… - Seminars in cell & …, 2021 - Elsevier
Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Signaling pathways in mammary gland development

L Hennighausen, GW Robinson - Developmental cell, 2001 - cell.com
Unlike most other organs, development of the mammary gland occurs predominantly after
birth, under the control of steroid and peptide hormones. Once the gland is established …

Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy

LM Arendt, C Kuperwasser - Journal of mammary gland biology and …, 2015 - Springer
The mammary gland undergoes dramatic post-natal growth beginning at puberty, followed
by full development occurring during pregnancy and lactation. Following lactation, the …

Mammary development in the embryo and adult: new insights into the journey of morphogenesis and commitment

CJ Watson, WT Khaled - Development, 2020 - journals.biologists.com
The mammary gland is a unique tissue and the defining feature of the class Mammalia. It is a
late-evolving epidermal appendage that has the primary function of providing nutrition for …

Signalling pathways implicated in early mammary gland morphogenesis and breast cancer

B Howard, A Ashworth - PLoS genetics, 2006 - journals.plos.org
Specification of mammary epithelial cell fate occurs during embryogenesis as cells
aggregate to form the mammary anlage. Within the embryonic mammary bud, a population …