Potential therapeutic targets and promising drugs for combating SARS‐CoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
As of April 9, 2020, a novel coronavirus (SARS‐CoV‐2) had caused 89,931 deaths and
1,503,900 confirmed cases worldwide, which indicates an increasingly severe and …

An overview on anti-COVID-19 drug achievements and challenges ahead

M Valipour, H Irannejad, H Keyvani - ACS Pharmacology & …, 2023 - ACS Publications
The appearance of several coronavirus pandemics/epidemics during the last two decades
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

Therapeutic Development and Drugs for the Treatment of COVID-19

VK Maurya, S Kumar, MLB Bhatt, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
Abstract SARS-CoV-2/novel coronavirus (2019-nCoV) is a new strain that has recently been
confirmed in Wuhan City, Hubei Province of China, and spreads to more than 165 countries …

Potential inhibitors of SARS-CoV-2: recent advances

G Jamalipour Soufi, S Iravani - Journal of Drug Targeting, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared in 2019 and is
the causative agent of the new pandemic viral disease COVID-19. The outbreak of COVID …

Coronavirus diseases 2019: current biological situation and potential therapeutic perspective

S Khan, H Tombuloglu, SE Hassanein… - European Journal of …, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) caused by a Severe Acute Respiratory
Syndrome Coronavirus-2 (SARS-CoV-2) was first reported in Wuhan, China at the end of …

The race to treat COVID-19: Potential therapeutic agents for the prevention and treatment of SARS-CoV-2

I Ahmad - European journal of medicinal chemistry, 2021 - Elsevier
The unforeseen emergence of coronavirus disease 2019 (COVID-19), a severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) at the Wuhan province of China in …

[HTML][HTML] Recent advances in developing small-molecule inhibitors against SARS-CoV-2

R Xiang, Z Yu, Y Wang, L Wang, S Huo, Y Li… - … Pharmaceutica Sinica B, 2022 - Elsevier
The COVID-19 pandemic caused by the novel SARS-CoV-2 virus has caused havoc across
the entire world. Even though several COVID-19 vaccines are currently in distribution …

Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2)-an update on the status

TM Abd El-Aziz, JD Stockand - Infection, Genetics and evolution, 2020 - Elsevier
Coronaviruses are a large group of viruses known to cause illnesses that vary between the
common cold and more severe diseases to include severe acute respiratory syndrome …

Tackling SARS-CoV-2: proposed targets and repurposed drugs

S Joshi, M Joshi, MS Degani - Future medicinal chemistry, 2020 - Taylor & Francis
The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in
February 2020, has currently infected more than 6 million people with fatalities near 371,000 …