Abstract Killer Immunoglobulin-like Receptor (KIR) genes may influence both resistance and
susceptibility to different autoimmune diseases, but their role in the pathogenesis of Multiple …

Killer Immunoglobulin-like Receptor (KIR) genes may affect both resistance and
susceptibility to autoimmune disorders, but their role in the pathogenesis of Multiple …

Killer cell immunoglobulin-like receptors (KIRs) are regulators of cytolytic activity of natural
killer and certain T cells through interactions with human leukocyte antigen (HLA) class I …

Objective: The objective of this study was to analyze whether inhibitory and activating killer
cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I alleles …

We investigated the role of the KIR loci and their HLA class I ligands in a large cohort of
African American multiple sclerosis (MS) patients (N= 907) and controls (N= 1456). No …

Multiple sclerosis (MS) is a disease in which we can recognize destruction of the myelin that
is around nerve cells of brain and spinal cord called as oligodendrocytes. Both genetic and …

A previous study has suggested that the combination KIR2DS2+/KIR2DL2-was related to
increased risk for systemic sclerosis (SSc), while others have failed to reproduce this finding …

Several lines of evidence implicate CD56bright NK cells in the pathogenesis of multiple
sclerosis (MS). This proposed immunoregulatory pathway involves already established …

Genetic factors have a great role in the pathogenesis of autoimmune diseases by
cooperating with environmental stimuli. Killer immunoglobulin-like receptors (KIRs) are cell …

To evaluate the possible effect of cell immunoglobulin-like receptors (KIRs) on viral infection
in multiple sclerosis (MS) patients, we performed genotyping of KIR2DL2 and his HLA-C1 …