purpose. To study the in vitro and in vivo interaction of chitosan nanoparticles (CSNPs), a
new particulate drug carrier, with epithelial cells on the ocular surface. methods. CSNPs …

Purpose. To assess the potential of chitosan (CS) nanoparticles for ocular drug delivery by
investigating their interaction with the ocular mucosa in vivo and also their toxicity in …

Present limitations in the management of extraocular diseases include the inability to
provide long-term extraocular drug delivery without compromising intraocular structures …

Purpose Nanoparticles are a promising alternative for ocular drug delivery, and our group
has proposed that they are especially suited for ocular mucosal disorders. The goal of the …

The purpose of this review is to provide the reader with an overview of the advances made
in ocular delivery of bioactive molecules by means of chitosan-based nanosystems, and …

This study evaluated in vitro and in vivo a colloidal nanosystem with the potential to deliver
drugs to the ocular surface. This nanosystem, liposome–chitosan nanoparticle complexes …

Purpose The goal of the present study was to synthesize mucoadhesive polymer–thiolated
chitosan (TCS) from chitosan (CS), then prepared CS/TCS-sodium alginate nanoparticles …

This paper presents an overview of the potential of chitosan‐based systems for improving
the retention and biodistribution of drugs applied topically onto the eye. Besides its low …

Purpose: To characterize nanoparticles produced by self-assembly of oppositely charged
polymers, cationic chitosan (CS), and anionic dextran sulfate (DS), for drug delivery to the …

Nanoscience and nanotechnology has caused important breakthroughs in different
therapeutic areas. In particular, the application of nanotechnology in ophthalmology has led …