A variety of findings seem to functionally link brainderived neurotrophic factor (BDNF))'and
neurotrophin3 (NT-3), while distinguishing both of these factors from the third member of the …

We have exploited a battery of approaches to address several controversies that have
accompanied the expansion of the nerve growth factor (NCF) family of neurotrophic factors …

The trkB gene codes for a receptor tyrosine kinase, which is essential for the development of
the peripheral nervous system. This receptor can be activated by three different …

trkB encodes a receptor tyrosine kinase activated by three neurotrophins—brain-derived
neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4/5. In vivo, three isoforms of …

The neurotrophins(nerve growth factor [NGF], brainderived neurotrophic factor [BDNF],
neurotrophin-3 [NT-31, and neurotrophin-4 [NT-41) have been defined by their ability to …

Models of activity-dependent synaptic plasticity, whether in the context of development or of
learning and memory, have long postulated the existence of extracellular signaling …

Neurotrophins are a family of soluble ligands that promote the survival and differentiation of
peripheral and central neurons and regulate synaptic function. The two neurotrophins, brain …

Accumulating evidence indicates that the Trk family of tyrosine protein kinase receptors, Trk
(also known as TrkA), TrkB, and TrkC, are responsible for mediating the trophic effects of the …

The neurotrophins brain‐derived neurotrophic factor (BDNF) and NT‐4/5 exert their trophic
effects on the nervous system via signaling through trkB receptors. These receptors occur as …

Summary trkB is a tyrosine protein kinase gene highly related to trk, a proto-oncogene that
encodes a receptor for nerve growth factor (NGF) and neurotrophin-3(NT-3). t&B expression …