[HTML][HTML] Immune determinants of COVID-19 disease presentation and severity

P Brodin - Nature medicine, 2021 - nature.com
Abstract COVID-19, caused by SARS-CoV-2 infection, is mild to moderate in the majority of
previously healthy individuals, but can cause life-threatening disease or persistent …

[HTML][HTML] Sex differences in immune responses that underlie COVID-19 disease outcomes

T Takahashi, MK Ellingson, P Wong, B Israelow… - Nature, 2020 - nature.com
There is increasing evidence that coronavirus disease 2019 (COVID-19) produces more
severe symptoms and higher mortality among men than among women,,,–. However …

[HTML][HTML] COVID-19 infection: the perspectives on immune responses

Y Shi, Y Wang, C Shao, J Huang, J Gan… - Cell Death & …, 2020 - nature.com
More than 100 years since the outbreak of the 1918 influenza pandemic, we now seem to
face another pandemic. The outbreak of the new coronavirus (SARS-CoV-2) infection is …

[HTML][HTML] A dynamic COVID-19 immune signature includes associations with poor prognosis

AG Laing, A Lorenc, I Del Molino Del Barrio, A Das… - Nature medicine, 2020 - nature.com
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …

The immunology and immunopathology of COVID-19

M Merad, CA Blish, F Sallusto, A Iwasaki - Science, 2022 - science.org
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

[HTML][HTML] Longitudinal analyses reveal immunological misfiring in severe COVID-19

C Lucas, P Wong, J Klein, TBR Castro, J Silva… - Nature, 2020 - nature.com
Recent studies have provided insights into the pathogenesis of coronavirus disease 2019
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …

[HTML][HTML] Distinguishing features of Long COVID identified through immune profiling

J Klein, J Wood, JR Jaycox, RM Dhodapkar, P Lu… - Nature, 2023 - nature.com
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …

[HTML][HTML] The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity

H Bolouri, C Speake, D Skibinski… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Despite a rapidly growing body of literature on coronavirus disease 2019
(COVID-19), our understanding of the immune correlates of disease severity, course, and …

Why do some people develop serious COVID-19 disease after infection, while others only exhibit mild symptoms?

M Ballow, CL Haga - The Journal of Allergy and Clinical Immunology: In …, 2021 - Elsevier
The year 2020 was a landmark year of a once-in-a-century pandemic of a novel coronavirus,
SARS-CoV-2 virus, that led to a rapidly spreading coronavirus disease (COVID-19). The …

[HTML][HTML] Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

C Phetsouphanh, DR Darley, DB Wilson, A Howe… - Nature …, 2022 - nature.com
A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection
develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here …