Intracellular pH is under strict control in myocardium; H+ are extruded from the cells by
sodium-dependent mechanisms, mainly Na+/H+ exchanger and Na+/HCO3− symport …

To elucidate the mechanisms controlling pHi in myocardium of the spontaneously
hypertensive rat (SHR), experiments were performed in papillary muscles (isometrically …

Intracellular pH (pHi) and developed pressure during hypercapnic acidosis were studied in
the spontaneously hypertensive rat (SHR) heart and Wistar-Kyoto controls. Developed …

Na+/H+ exchange (NHE) represents a major mechanism for intracellular pH regulation,
particularly in the ischemic myocardium. NHE has also been shown to be important in the …

The effect of angiotensin II (Ang II) on the activity of the cardiac Na+-independent Cl−-
HCO3− exchanger (anionic exchanger [AE]) was explored in cat papillary muscles. pHi was …

The effect of angiotensin II (Ang II) on the activity of the cardiac Na+-independent Cl−-
HCO3− exchanger (anionic exchanger [AE]) was explored in cat papillary muscles. pHi was …

We compared the effects of endothelin-1 (ET-1) on intracellular pH, intracellular [Ca2+] i,
and cell contraction in hypertrophied adult ventricular myocytes from ascending aortic …

Objective: The aim was to examine the regulation of the cardiac Na+-independent
Cl−/HCO3− exchanger (AE) mRNA isoform expression in association to the enhanced AE …

Plasma membrane anion exchangers (AEs) regulate myocardial intracellular pH (pHi) by
Na+-independent Cl−/HCO3− exchange. Angiotensin II (Ang II) activates protein kinase C …

Cardiac hypertrophy (CH) is a major risk factor for cardiac death and commonly precedes
the development of heart failure (HF). This is motivating the search for novel …