Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics

I Giegling, L Hosak, R Mössner, A Serretti… - The world journal of …, 2017 - Taylor & Francis
Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general
population. The relative contribution of genetic factors has been estimated to be up to 80 …

Genetics of schizophrenia: new findings and challenges

PV Gejman, AR Sanders… - Annual review of …, 2011 - annualreviews.org
The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …

Schizophrenia genetics: emerging themes for a complex disorder

DH Kavanagh, KE Tansey, MC O'Donovan… - Molecular …, 2015 - nature.com
After two decades of frustration, genetic studies of schizophrenia have entered an era of
spectacular success. Advances in genotyping technologies and high throughput …

Genetics of schizophrenia

I Escudero, M Johnstone - Current psychiatry reports, 2014 - Springer
The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

M Ayalew, H Le-Niculescu, DF Levey, N Jain… - Molecular …, 2012 - nature.com
We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

[HTML][HTML] New findings in the genetics of schizophrenia

L Hosak - World journal of psychiatry, 2013 - ncbi.nlm.nih.gov
New findings in schizophrenia genetics are based on genome-wide association studies
(GWAS), research into DNA copy number variations (CNVs), and endophenotypes. More …

Dissecting the genetic complexity of schizophrenia

M Karayiorgou, JA Gogos - Molecular psychiatry, 1997 - nature.com
Twin, adoption and family studies have provided overwhelming but indirect evidence for a
significant genetic contribution to the etiology of schizophrenia. More recent studies …

[HTML][HTML] Genetics of schizophrenia: overview of methods, findings and limitations

MG Henriksen, J Nordgaard… - Frontiers in human …, 2017 - frontiersin.org
Genetics constitute a crucial risk factor to schizophrenia. In the last decade, molecular
genetic research has produced novel findings, infusing optimism about discovering the …

Genomic findings in schizophrenia and their implications

MJ Owen, SE Legge, E Rees, JTR Walters… - Molecular …, 2023 - nature.com
There has been substantial progress in understanding the genetics of schizophrenia over
the past 15 years. This has revealed a highly polygenic condition with the majority of the …

Genomic approaches to schizophrenia

MJ Owen - Clinical therapeutics, 2005 - Elsevier
BACKGROUND:: Genetic epidemiologic studies suggest that individual variation in
susceptibility to schizophrenia is substantially genetic. However, like other common …