The interplay between fear expression and fear extinction provides an important prerequisite
for adequate coping with aversive encounters. Current models propose that extinction of …

To maximize their chances of survival, animals need to rapidly and efficiently respond to
aversive situations. These responses can be classified as active or passive and depend on …

The cannabinoid receptor type 1 (CB1) is abundantly expressed in the central nervous
system where it negatively controls the release of several neurotransmitters. CB1 activity …

Cannabinoids affect various behavioral processes, including emotion, learning and memory,
which may bspecifically regulated through the CB1 receptors. The exact role CB1 receptors …

Cannabinoid receptors type 1 (CB1) play a central role in both short-term and long-term
extinction of auditory-cued fear memory. The molecular mechanisms underlying this function …

The endogenous cannabinoid (eCB) system represents a major therapeutic target for the
treatment of a variety of anxiety-related disorders. A recent study has demonstrated that …

Previous studies have implicated cannabinoids in extinction of conditioned fear. We have
recently showed that intraventricular infusion of the phytocannabinoid cannabidiol (CBD) …

Endocannabinoids are critically involved in the extinction of fear memory. Here we
examined the effects of repeated cannabinoid administration on the extinction of fear …

We studied the effects of cannabinoids on contextual conditioned fear responses. CB1
knockout and wild-type (CD1) mice were exposed to a brief session of electric shocks, and …

Neurocognitive effects of cannabinoids have been extensively studied with a focus on CB1
cannabinoid receptors because CB1 receptors have been considered the major …