The SWI/SNF complex creates loop domains in DNA and polynucleosome arrays and can disrupt DNA-histone contacts within these domains
DP Bazett-Jones, J Côté, CC Landel… - … and cellular biology, 1999 - Am Soc Microbiol
To understand the mechanisms by which the chromatin-remodeling SWI/SNF complex
interacts with DNA and alters nucleosome organization, we have imaged the SWI/SNF …
interacts with DNA and alters nucleosome organization, we have imaged the SWI/SNF …
Inverted factor access and slow reversion characterize SWI/SNF-altered nucleosome dimers
NP Ulyanova, GR Schnitzler - Journal of Biological Chemistry, 2007 - ASBMB
Human SWI/SNF (hSWI/SNF) is an ATP-dependent chromatin remodeling complex with
important functions in activation and repression of cellular genes. Previously, we showed …
important functions in activation and repression of cellular genes. Previously, we showed …
Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells
Accessibility of the genomic regulatory information is largely controlled by the nucleosome-
organizing activity of transcription factors (TFs). While stimulus-induced TFs bind to genomic …
organizing activity of transcription factors (TFs). While stimulus-induced TFs bind to genomic …
Insights into distinct regulatory modes of nucleosome positioning
Z Dai, X Dai, Q Xiang, J Feng, Y Deng, J Wang - BMC genomics, 2009 - Springer
Background The nucleosome is the fundamental unit of eukaryotic genomes. Experimental
evidence suggests that the genomic DNA sequence and a variety of protein factors …
evidence suggests that the genomic DNA sequence and a variety of protein factors …
[图书][B] Investigation of the Mechanism Underlying Nucleosome Invasion by Nucleosome-Displacing Factors
H Chen - 2022 - search.proquest.com
DNA sequence specific transcription factors (TFs) are key regulators for gene regulation. In
prokaryotes, TFs can easily access their DNA binding motifs to activate or repress …
prokaryotes, TFs can easily access their DNA binding motifs to activate or repress …
Routes to DNA accessibility: alternative pathways for nucleosome unwinding
The dynamic packaging of DNA into chromatin is a key determinant of eukaryotic gene
regulation and epigenetic inheritance. Nucleosomes are the basic unit of chromatin, and …
regulation and epigenetic inheritance. Nucleosomes are the basic unit of chromatin, and …
Solution AFM studies of human Swi-Snf and its interactions with MMTV DNA and chromatin
H Wang, R Bash, SM Lindsay, D Lohr - Biophysical journal, 2005 - cell.com
ATP-dependent nucleosome remodeling complexes are crucial for relieving nucleosome
repression during transcription, DNA replication, recombination, and repair. Remodeling …
repression during transcription, DNA replication, recombination, and repair. Remodeling …
DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC
Y Zhang, CL Smith, A Saha, SW Grill, S Mihardja… - Molecular cell, 2006 - cell.com
ATP-dependent chromatin-remodeling complexes (remodelers) modulate gene transcription
by regulating the accessibility of highly packaged genomic DNA. However, the molecular …
by regulating the accessibility of highly packaged genomic DNA. However, the molecular …
Nucleosomes as allosteric scaffolds for genetic regulation
Highlights•Nucleosomes exhibit diverse types of motion, such as sliding, DNA unwrapping,
and disassembly.•The energy landscape of nucleosomes contains multitude of metastable …
and disassembly.•The energy landscape of nucleosomes contains multitude of metastable …
Direct Quantification of Gene Regulation by Transcription-Factor Binding at an Endogenous Gene Locus
Gene activity is controlled by the binding of transcription factors (TFs) to the regulatory
sequence of the gene, yet a direct in situ mapping from TF binding to mRNA production of a …
sequence of the gene, yet a direct in situ mapping from TF binding to mRNA production of a …