The structure of the SWI/SNF-remodeled nucleosome was characterized with single base-
pair resolution by mapping the contacts of specific histone fold residues with nucleosomal …

The mobilization of nucleosomes by the ATP-dependent remodeler INO80 is quite different
from another remodeler (SWI/SNF) that is also involved in gene activation. Unlike that …

The nucleosome remodeling factor NURF is a four-subunit, ISWI-containing chromatin
remodeling complex that catalyzes nucleosome sliding in an ATP-dependent fashion …

It has become increasingly apparent that eukaryotic cells possess machinery that modifies
chromatin structure and that this machinery contributes to the regulation of gene expression …

Elucidating the mechanisms by which ATP-dependent chromatin remodeling enzymes
disrupt nucleosome structure is essential to understanding how chromatin states are …

Genomic processes like transcription initiation typically involve the alteration of nucleosome
structure, to expose DNA elements for regulatory factor binding. Nucleosome …

Recent studies have shown that two nucleosome-remodeling complexes, NURF and
CHRAC, open chromatin for transcription and replication by using their common catalytic …

We investigate how DNA sequence, ATP-dependent chromatin remodeling and nucleosome-
depleted 'barriers' co-operate to determine the kinetics of nucleosome organization, in a …

Chromatin remodeling complexes help regulate the structure of chromatin to facilitate
transcription. The multisubunit human (h) SWI-SNF complex has been shown to remodel …

The packaging of DNA into nucleosomes impedes the binding and access of molecules
involved in its processing. The SWI/SNF multi-protein assembly, found in yeast, is one of …