SPARC suppresses apoptosis of idiopathic pulmonary fibrosis fibroblasts through constitutive activation of β-catenin

W Chang, K Wei, SS Jacobs, D Upadhyay… - Journal of Biological …, 2010 - ASBMB
Idiopathic pulmonary fibrosis (IPF) is a poorly understood progressive disease characterized
by the accumulation of scar tissue in the lung interstitium. A hallmark of the disease is areas …

Translating JAKs to jakinibs

M Gadina, DA Chisolm, RL Philips… - The Journal of …, 2020 - journals.aai.org
The discovery of JAKs and STATs and their roles in cytokine and IFN action represented a
significant basic advance and a new paradigm in cell signaling. This was quickly followed by …