Type 2 diabetes mellitus (T2DM), currently an epidemic, is expected to disproportionately
affect developing countries in the coming decades [1]. Thus, primary prevention of T2DM is a …

1. Background Metabolomics–the systematic study of chemical processes involving
metabolites, small molecule substrates, intermediates, and products of cell metabolism [1] …

Cardiometabolic dieases are the main causes of morbidity and mortality worldwide. Despite
large clinical and basic research efforts to improve the understanding of the molecular …

There have been considerable improvements in therapeutics for chronic diseases. However,
the maximum benefit of these or other options are hard to achieve in practice, due in part to …

Metabolomics is the systematic study of the unique chemical fingerprints of small molecules
or metabolite profiles that are related to a variety of cellular metabolic processes in a cell …

The high prevalence of diabetes and diabetic complications has caused a huge burden on
the modern society. Although scientific advances have led to effective strategies for …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, but their
molecular etiology remains poorly understood, in part because they develop slowly as a …

Metabolic characterization of type 2 diabetes mellitus (T2DM) is crucial for the identification
of individuals at risk for developing diabetes and T2DM-related vascular complications as …

Numerous molecular screening strategies have recently been developed to measure the
chemical diversity of a population's biofluids with the ultimate aim to provide clinicians …

BACKGROUND Metabolomics, the systematic analysis of low molecular weight biochemical
compounds in a biological specimen, has been increasingly applied to biomarker discovery …