[HTML][HTML] Sex-related overactivation of NLRP3 inflammasome increases lethality of the male COVID-19 patients
H Zhang, Y Tang, J Tao - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The COVID-19 pandemic, caused by SARS-CoV-2 infection, remains a dramatic threat to
human life and economic well-being worldwide. Significant heterogeneity in the severity of …
human life and economic well-being worldwide. Significant heterogeneity in the severity of …
[HTML][HTML] Immunoinflammatory, thrombohaemostatic, and cardiovascular mechanisms in COVID-19
The global coronavirus disease 2019 (COVID-19) pandemic has deranged the recent
history of humankind, afflicting more than 27 million individuals to date. While the majority of …
history of humankind, afflicting more than 27 million individuals to date. While the majority of …
[HTML][HTML] Neutrophils and neutrophil extracellular traps drive necroinflammation in COVID-19
The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an
urgent need for novel therapeutic strategies to combat potentially fatal complications …
urgent need for novel therapeutic strategies to combat potentially fatal complications …
[HTML][HTML] Mechanisms of COVID-19 thrombosis in an inflammatory environment and new anticoagulant targets
H Liu, T Hu, C Zhang, X Chen, S Zhang… - American journal of …, 2021 - ncbi.nlm.nih.gov
COVID-19 is widely epidemic in the world and poses a great threat to our life. Coagulopathy
is one of the major characteristics in the COVID-19 patients. A growing number of studies …
is one of the major characteristics in the COVID-19 patients. A growing number of studies …
[HTML][HTML] COVID-19 and the Concept of Thrombo-Inflammation: Review of the Relationship between Immune Response, Endothelium and Coagulation
E de Maistre, P Savard, PG Guinot - Journal of Clinical Medicine, 2023 - mdpi.com
COVID-19, caused by the SARS-CoV-2 virus, has revealed a complex interplay between
inflammation and coagulation, leading to the emergence of the concept of thrombo …
inflammation and coagulation, leading to the emergence of the concept of thrombo …
[HTML][HTML] A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS
L Reyes, MA Sanchez-Garcia, T Morrison… - Wellcome open …, 2021 - ncbi.nlm.nih.gov
Background: Acute respiratory distress syndrome (ARDS) is a severe critical condition with a
high mortality that is currently in focus given that it is associated with mortality caused by …
high mortality that is currently in focus given that it is associated with mortality caused by …
[HTML][HTML] Thrombosis in COVID-19 infection: Role of platelet activation-mediated immunity
MB Fard, SB Fard, S Ramazi, A Atashi, Z Eslamifar - Thrombosis Journal, 2021 - Springer
Background Thrombosis plays an important role in the Coronavrus Disease 2019 (COVID-
19) infection-related complications such as acute respiratory distress syndrome and …
19) infection-related complications such as acute respiratory distress syndrome and …
Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loop
A Yaqinuddin, J Kashir - Medical hypotheses, 2020 - Elsevier
Most COVID-19 infected individuals present with mild flu-like symptoms; however, 5–10% of
cases suffer from life-threatening pneumonia and respiratory failure. The pathogenesis of …
cases suffer from life-threatening pneumonia and respiratory failure. The pathogenesis of …
Interleukin-1RA mitigates SARS-CoV-2–induced inflammatory lung vascular leakage and mortality in humanized K18-hACE-2 mice
Objective: SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection is a
major cause of morbidity and mortality, often as a result of acute respiratory distress …
major cause of morbidity and mortality, often as a result of acute respiratory distress …
Thrombo-inflammation in long COVID–the elusive key to post-infection sequelae?
Long COVID is a public health emergency affecting millions of people worldwide,
characterized by heterogenous symptoms across multiple organs systems. Here, we discuss …
characterized by heterogenous symptoms across multiple organs systems. Here, we discuss …