A double-edged sword: antibody-mediated procoagulant platelets in COVID-19
SL Millington-Burgess, MT Harper - Platelets, 2021 - Taylor & Francis
The past year has demonstrated the power of collaborative scientific efforts in rapidly
developing vaccines to curb the SARS-CoV-2 pandemic and repurposed drugs to improve …
developing vaccines to curb the SARS-CoV-2 pandemic and repurposed drugs to improve …
Integrated analysis of transcriptomic data reveals the platelet response in COVID-19 disease
COVID-19 is associated with an increased risk of thrombotic events. However, the
pathogenesis of these complications is unclear and reports on platelet infection and …
pathogenesis of these complications is unclear and reports on platelet infection and …
[HTML][HTML] Potential role of platelets in COVID‐19: implications for thrombosis
M Koupenova - Research and Practice in Thrombosis and …, 2020 - Elsevier
For the past 150 years, platelets have been recognized as the major blood component that
mediates hemostasis and thrombosis. In more recent years, however, we have come to …
mediates hemostasis and thrombosis. In more recent years, however, we have come to …
Heparin-induced thrombocytopenia in COVID-19
P Lingamaneni, S Gonakoti, K Moturi… - … high impact case …, 2020 - journals.sagepub.com
COVID-19 (coronavirus disease-2019) infection is a highly prothrombotic state, resulting
from a dysregulation of the coagulation cascade. Therefore, thromboprophylaxis is strongly …
from a dysregulation of the coagulation cascade. Therefore, thromboprophylaxis is strongly …
[HTML][HTML] Platelet and Monocyte Microvesicles as Potential Biomarkers of COVID-19 Severity: A Cross-Sectional Analysis
N Nunki, Y Hernaningsih, P Wardhani… - Annals of laboratory …, 2024 - ncbi.nlm.nih.gov
Background Coronavirus disease (COVID-19) induces inflammation, coagulopathy following
platelet and monocyte activation, and fibrinolysis, resulting in elevated D-dimer levels …
platelet and monocyte activation, and fibrinolysis, resulting in elevated D-dimer levels …
Antibody‐mediated procoagulant platelet formation in COVID‐19 is AKT dependent
Background Thromboembolic events are frequently reported in patients infected with the
SARS‐CoV‐2. Recently, we observed that platelets from patients with severe COVID‐19 …
SARS‐CoV‐2. Recently, we observed that platelets from patients with severe COVID‐19 …
[HTML][HTML] The roles of platelets in COVID-19-associated coagulopathy and vaccine-induced immune thrombotic thrombocytopenia
Abstract In coronavirus disease 2019 (COVID-19), multiple thromboinflammatory events
contribute to the pathophysiology, including coagulation system activation, suppressed …
contribute to the pathophysiology, including coagulation system activation, suppressed …
COVID-19 induces a hyperactive phenotype in circulating platelets
SP Comer, S Cullivan, PB Szklanna, L Weiss… - PLoS …, 2021 - journals.plos.org
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date …
Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date …
Fibrinogen binding to histones in circulation protects against adverse cellular and clinical outcomes
JM Toh, J Yong, ST Abrams, L Wang, J Schofield… - Journal of Thrombosis …, 2024 - Elsevier
Background Circulating histones are released by extensive tissue injury or cell death and
play important pathogenic roles in critical illnesses. Their interaction with circulating plasma …
play important pathogenic roles in critical illnesses. Their interaction with circulating plasma …
Altered platelet and coagulation function in moderate-to-severe COVID-19
To reveal if coagulopathies relate to the course of COVID-19, we examined 255 patients with
moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs …
moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs …