Immune Profiling of COVID-19 in Correlation with SARS and MERS

BA Khalil, SB Shakartalla, S Goel, B Madkhana… - Viruses, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a major complication of the respiratory illness
coronavirus disease 2019, with a death rate reaching up to 40%. The main underlying cause …

Complex immune deregulation in severe COVID-19: More than a mechanism of pathogenesis

EJ Giamarellos-Bourboulis - EBioMedicine, 2021 - thelancet.com
The generated impression early at the beginning of the pandemic by SARS-CoV-2 (also
called COVID-19) was that severe COVID-19 is due to a cytokine storm with the over …

[HTML][HTML] Cytokine storm in novel coronavirus disease (COVID-19): expert management considerations

Y Mehta, SB Dixit, KG Zirpe… - Indian journal of critical …, 2020 - ncbi.nlm.nih.gov
Background Cytokine storm is caused by the colossal release of proinflammatory cytokines
[eg, IL (interleukin)-2, IL-6, IL-8 TNF (tumor necrosis factor)-α, etc.] causing dysregulated …

Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. The clinical
presentations of the SARS-CoV-2 infection are widely variable and treatment strategies for …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Immune dysregulation and system pathology in COVID-19

M Jamal, HI Bangash, M Habiba, Y Lei, T Xie, J Sun… - Virulence, 2021 - Taylor & Francis
ABSTRACT The coronavirus disease 19 (COVID-19) caused by the novel coronavirus
known as SARS-CoV-2 has caused a global public health crisis. As of 7 January 2021 …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
In 2019–2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent
of a several acute respiratory infection named COVID-19, which is causing a worldwide …

Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic …

Immune signature of covid-19: In-depth reasons and consequences of the cytokine storm

P Niedźwiedzka-Rystwej, A Majchrzak… - International Journal of …, 2022 - mdpi.com
In the beginning of the third year of the fight against COVID-19, the virus remains at least still
one step ahead in the pandemic “war”. The key reasons are evolving lineages and …