Major psychiatric traits are genetically inter-correlated with one another, but it not well known
which genes play pleiotropic effects across different traits. We curated and compared genes …

Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …

The availability of genome-wide genetic data on hundreds of thousands of people has led to
an equally rapid growth in methodologies available to analyse these data. While the …

Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …

Substantial genetic liability is shared across psychiatric disorders but less is known about
risk variants that are specific to a given disorder. We used multi-trait conditional and joint …

BackgroundPsychiatric disorders and related intermediate phenotypes are highly heritable
and have a complex, overlapping polygenic architecture. A large-scale genome-wide …

Understanding which biological pathways are specific versus general across diagnostic
categories and levels of symptom severity is critical to improving nosology and treatment of …

Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple
genetic associations with such disorders, but better methods are needed to derive the …

Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental
disorder that results from the interaction of both genetic and environmental risk factors …

After more than 10 years of accumulated efforts, genome-wide association studies (GWAS)
have led to many findings, most of which have been deposited into the GWAS Catalog …