Mesenchymal stem cells (MSCs) offer significant therapeutic promise for various
regenerative therapies. However, MSC-based therapy for injury exhibits low efficacy due to …

Abstract Introduction Mesenchymal stem cells (MSCs) are widely investigated in clinical
researches to treat various diseases. Classic culture medium for MSCs, even for clinical use …

Expansion in vitro prior to mesenchymal stem cells (MSCs) application is a necessary
process. Functional and genomic stability has a crucial role in stem-cell-based therapies …

Directed differentiation of induced pluripotent stem cells (iPSCs) towards specific lineages
remains a major challenge in regenerative medicine, while there is a growing perception …

Despite the wide use of mesenchymal stromal cells (MSCs) for paracrine support in clinical
trials, their variable and heterogeneous supporting activity pose major challenges. While …

Background Mesenchymal stem cells (MSCs) hold great promise for the treatment of difficult
diseases. As MSCs represent a rare cell population, ex vivo expansion of MSCs is …

Simple Summary With the aim of improving the therapeutic potential of mesenchymal
stromal/stem cells (MSCs), we analyzed miRNA expression to investigate the effects of …

Background Because of the heterogeneity of human mesenchymal stem cells (MSCs),
methods for cell expansion in culture and the effects on gene expression are critical factors …

We aim to identify levels of signal factors secreted by MSCs cultured in 2D monolayers (2D‐
MSCs), spheroids (spheroids MSCs), and cocultures of microvesicles (MVs) derived from 2D …

MSCs are a population of adult stem cells that is a promising source for therapeutic
applications. These cells can be isolated from the bone marrow and can be easily separated …