Cancer is one of the leading causes of death in the industrialized world and represents a
tremendous social and economic burden. As conventional therapies fail to provide a …

Over the years, conventional cancer treatments, such as chemotherapy with only a limited
specificity for tumors, have undergone significant improvement. Moreover, newer therapies …

Conventional chemotherapies have some limitations, including the lack of selectivity, high
toxicity to normal tissues, multidrug resistance, and tumor relapse. Recently, great progress …

Cancer is a devastating disease and a large socio-economic burden. Novel therapeutic
solutions are on the rise, although a cure remains elusive. Application of microorganisms …

Bacteria-mediated tumor therapy using Salmonella enterica serovar Typhimurium is a
therapeutic option with great potential. Numerous studies explored the potential of …

In the course of evolution, bacteria from the genus Salmonella adapted to survive and
multiply in a ver‑tebrate host. Skillful use of bacterial inter actions with the host immune …

The potential of bacteria-mediated tumor therapy (BMTT) is highlighted by more than a
century of investigation. Attenuated Salmonella has prevailed as promising therapeutic …

Obligate or facultative anaerobic bacteria such as Bifidobacterium, Clostridium, Salmonella,
or Escherichia coli specifically colonize and proliferate inside tumor tissues and inhibit tumor …

Bacterial-mediated cancer therapy (BMCT) has become a hot topic in the area of antitumor
treatment. Salmonella has been recommended to specifically colonize and proliferate inside …

In recent years, cancer immunotherapy has undergone great advances because of our
understanding of the immune response and the mechanisms through which tumor cells …