Our understanding of radiation-induced cellular damage has greatly improved over the past
few decades. Despite this progress, there are still many obstacles to fully understand how …

The aim of this report is to present the spectrum of initial radiation-induced cellular DNA
damage [with particular focus on non-double-strand break (DSB) damage] generated by …

Ionising radiation induced DNA damage and subsequent biological responses to it depend
on the radiation's track-structure and its energy loss distribution pattern. To investigate the …

Characterising and predicting the effects of ionising radiation on cells remains challenging,
with the lack of robust models of the underlying mechanism of radiation responses providing …

Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are
widely used when dosimetry is the matter of investigation. The scientific community has …

Several models and theories are reviewed that incorporate the idea of radiation-induced
lesions (repairable and/or irreparable) that can be related to molecular lesions in the DNA …

Abstract Carlson, DJ, Stewart, RD, Semenenko, VA and Sandison, GA Combined Use of
Monte Carlo DNA Damage Simulations and Deterministic Repair Models to Examine …

The biophysical simulation code PARTRAC enables, by combining track structure
calculations with DNA models on diverse genomic scales, prediction of DNA damage yields …

Track structure Monte Carlo simulations are a useful tool to investigate the damage induced
to DNA by ionizing radiation. These simulations usually rely on simplified geometrical …

DNA is a key-target for genotoxic stress. Hence, the knowledge of induction and repair rate
of DNA damage are crucial to describe and predict the impact of stress situations …