NPR-C: a component of the natriuretic peptide family with implications in human diseases

S Rubattu, S Sciarretta, A Morriello, C Calvieri… - Journal of molecular …, 2010 - Springer
The natriuretic peptide (NP) family includes atrial natriuretic peptide (ANP), B-type natriuretic
peptide, C-type natriuretic peptide and their receptors NPR-A, NPR-B and NPR-C. The …

Variable number of tandem repeat of the 5′-flanking region of type-C human natriuretic peptide receptor gene influences blood pressure levels in obesity-associated …

N Aoi, M Soma, T Nakayama, D Rahmutula… - Hypertension …, 2004 - jstage.jst.go.jp
The gene for natriuretic peptides receptor C (NPRC), which is a candidate susceptibility
gene for essential hypertension (EH) or obese hypertension, plays a key role in the …

[HTML][HTML] Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis

P Willeit, S Kaptoge, P Welsh… - The lancet Diabetes & …, 2016 - thelancet.com
Background Guidelines for primary prevention of cardiovascular diseases focus on
prediction of coronary heart disease and stroke. We assessed whether or not measurement …

Genome-Wide Association Analysis of Plasma B–Type Natriuretic Peptide in Blacks: The Jackson Heart Study

SK Musani, ER Fox, A Kraja, A Bidulescu… - Circulation …, 2015 - Am Heart Assoc
Background—Numerous experimental studies suggest that B-type natriuretic peptide (BNP)
is cardioprotective; however, in clinical studies, higher plasma BNP concentrations have …

Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner

PM Oliver, SWM John, KE Purdy… - Proceedings of the …, 1998 - National Acad Sciences
Activation of the natriuretic peptide system lowers blood pressure and causes the excretion
of salt. Atrial natriuretic peptide and B-type natriuretic peptide are the humoral mediators of …

Sex‐specific associations of obesity and N‐terminal pro‐B‐type natriuretic peptide levels in the general population

N Suthahar, WC Meijers, JE Ho… - European journal of …, 2018 - Wiley Online Library
Background Obese subjects have lower natriuretic peptide levels, but males and females
have different anthropometric characteristics and fat distribution. Whether obesity …

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites

NL Pereira, N Tosakulwong, CG Scott… - Circulation …, 2015 - Am Heart Assoc
Background—The goal of this study was to identify genetic determinants of plasma N-
terminal proatrial natriuretic peptide (NT-proANP) in the general community by performing a …

Natriuretic peptide clearance receptor alleles and susceptibility to abdominal adiposity

R Sarzani, P Strazzullo, F Salvi, R Iacone… - Obesity …, 2004 - Wiley Online Library
Objective: To test the association of the C (− 55) A polymorphism of the natriuretic peptide
clearance receptor (NPRC) with blood pressure (BP), overweight/obesity, and body fat …

Knockdown of natriuretic peptide receptor-A enhances receptor C expression and signalling in vascular smooth muscle cells

Y Li, P Madiraju… - Cardiovascular research, 2012 - academic.oup.com
Aims Natriuretic peptide receptor-A (NPR-A) knockout mice exhibited an increased blood
pressure that may also be attributed to the up-regulation of NPR-C and associated …

The genetic contribution of the natriuretic peptide system to cardiovascular diseases

T Nakayama - Endocrine journal, 2005 - jstage.jst.go.jp
Three types of natriuretic peptides (NP) have been isolated: atrial natriuretic peptide (ANP),
brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The NP family elicits a …