What is the potential function of microRNAs as biomarkers and therapeutic targets in COVID-19?

A Guterres, CH de Azeredo Lima, RL Miranda… - Infection, genetics and …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19,
a pandemic associated with substantial morbidity and mortality. Despite of this, no vaccine …

Role of the MicroRNAs in the pathogenic mechanism of painful symptoms in long COVID: systematic review

S Reyes-Long, JL Cortés-Altamirano… - International Journal of …, 2023 - mdpi.com
The ongoing pandemic of COVID-19 has caused more than 6.7 million tragic deaths, plus, a
large percentage of people who survived it present a myriad of chronic symptoms that last …

Potential therapeutic approaches of microRNAs for COVID-19: challenges and opportunities

A Farshbaf, N Mohtasham, R Zare… - Journal of oral biology …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) emerges as current outbreak cause by
Novel Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). This infection …

SARS-CoV2 infection induce miR-155 expression and skewed Th17/Treg balance by changing SOCS1 level: A clinical study

MS Soltani-Zangbar, M Hajivalili, D Daneshdoust… - Cytokine, 2023 - Elsevier
Background One of the regulators in severe acute respiratory syndrome coronavirus2
(SARS-CoV2) infection is miRNAs. In COVID-19 patients, immunological responses to …

Implications of the virus-encoded miRNA and host miRNA in the pathogenicity of SARS-CoV-2

Z Liu, J Wang, Y Xu, M Guo, K Mi, R Xu, Y Pei… - arXiv preprint arXiv …, 2020 - arxiv.org
The outbreak of COVID-19 caused by SARS-CoV-2 has rapidly spread worldwide and has
caused over 1,400,000 infections and 80,000 deaths. There are currently no drugs or …

Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …

Role of SARS-CoV-2 in altering the RNA-binding protein and miRNA-directed post-transcriptional regulatory networks in humans

R Srivastava, SV Daulatabad, M Srivastava… - International journal of …, 2020 - mdpi.com
The outbreak of a novel coronavirus SARS-CoV-2 responsible for the COVID-19 pandemic
has caused a worldwide public health emergency. Due to the constantly evolving nature of …

Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 world-wide isolates delineated the mystery behind the epic …

MAAK Khan, MRU Sany, MS Islam… - Frontiers in genetics, 2020 - frontiersin.org
A detailed understanding of the molecular mechanism of SARS-CoV-2 pathogenesis is still
elusive, and there is a need to address its deadly nature and to design effective …

Non-coding RNAs and SARS-related coronaviruses

H Henzinger, DA Barth, C Klec, M Pichler - Viruses, 2020 - mdpi.com
The emergence of SARS-CoV-2 in 2019 has caused a major health and economic crisis
around the globe. Gaining knowledge about its attributes and interactions with human host …

Alterations in circulating miRNA levels after infection with SARS-CoV-2 could contribute to the Development of Cardiovascular diseases: what we know so far

M Pieri, P Vayianos, V Nicolaidou, K Felekkis… - International Journal of …, 2023 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and poses significant complications for …