[HTML][HTML] miRNA-223 as a regulator of inflammation and NLRP3 inflammasome, the main fragments in the puzzle of immunopathogenesis of different inflammatory …

S Houshmandfar, A Saeedi-Boroujeni… - Naunyn-schmiedeberg's …, 2021 - Springer
Millions of people around the world are involved with COVID-19 due to infection with SARS-
CoV-2. Virological features of SARS-CoV-2, including its genomic sequence, have been …

[HTML][HTML] miRCOVID-19: potential targets of human miRNAs in SARS-CoV-2 for RNA-based drug discovery

T Alam, L Lipovich - Non-coding RNA, 2021 - mdpi.com
Sense-antisense interactions of long and short RNAs in human cells are integral to post-
transcriptional gene regulation, in particular that of mRNAs by microRNAs. Many viruses …

Downregulation of microRNA-146a in diabetes, obesity and hypertension may contribute to severe COVID-19

J Roganović - Medical Hypotheses, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is able to
produce an excessive host immune reaction and may leads to severe disease-a life …

[HTML][HTML] MicroRNAs and long non-coding RNAs as potential candidates to target specific motifs of SARS-CoV-2

L Natarelli, L Parca, T Mazza, C Weber, F Virgili… - Non-coding RNA, 2021 - mdpi.com
The respiratory system is one of the most affected targets of SARS-CoV-2. Various therapies
have been utilized to counter viral-induced inflammatory complications, with diverse success …

[HTML][HTML] Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection

MDS Demirci, A Adan - PeerJ, 2020 - peerj.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression found in more
than 200 diverse organisms. Although it is still not fully established if RNA viruses could …

In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR

J Gasparello, E d'Aversa, G Breveglieri… - International …, 2021 - Elsevier
One of the major clinical features of COVID-19 is a hyperinflammatory state, which is
characterized by high expression of cytokines (such as IL-6 and TNF-α), chemokines (such …

[HTML][HTML] The potential use of microRNAs as a therapeutic strategy for SARS-CoV-2 infection

J Hu, J Stojanović, S Yasamineh, P Yasamineh… - Archives of …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). To date, there is no effective therapeutic approach …

[HTML][HTML] Computational analysis of targeting SARS-CoV-2, viral entry proteins ACE2 and TMPRSS2, and interferon genes by host microRNAs

JB Pierce, V Simion, B Icli, D Perez-Cremades… - Genes, 2020 - mdpi.com
Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
responsible for coronavirus disease 2019 (COVID-19), has led to a global pandemic …

In silico identification of potential miRNAs-mRNA inflammatory networks implicated in the pathogenesis of COVID-19

SH Sheikhshabani, Z Amini-Farsani, P Modarres… - Human Gene, 2023 - Elsevier
COVID-19 has been found to affect the expression profile of several mRNAs and miRNAs,
leading to dysregulation of a number of signaling pathways, particularly those related to …

[HTML][HTML] High affinity of host human microRNAs to SARS-CoV-2 genome: An in silico analysis

S Jafarinejad-Farsangi, MM Jazi… - Non-coding RNA …, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) caused by a novel
betacoronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …