Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960

M Worobey, M Gemmel, DE Teuwen, T Haselkorn… - Nature, 2008 - nature.com
Human immunodeficiency virus type 1 (HIV-1) sequences that pre-date the recognition of
AIDS are critical to defining the time of origin and the timescale of virus evolution,. A viral …

HIV causes aids

W Blattner, RC Gallo, HM Temin - Science, 1988 - science.org
AIDS, a new disease, was first recogzed in 1981, clustered in male homosexuals,
intravenous drug abusers, and hemophiliacs in the United States and among sexually active …

AIDS: an international perspective

P Piot, FA Plummer, FS Mhalu, JL Lamboray, J Chin… - Science, 1988 - science.org
The acquired immunodeficiency syndrome (AIDS) and infection with the human
immunodeficiency virus type 1 (HIV-1) constitute a worldwide public health problem …

Phylogeny and the origin of HIV-1

A Rambaut, DL Robertson, OG Pybus, M Peeters… - Nature, 2001 - nature.com
The origin of human immunodeficiency virus type 1 (HIV-1) is controversial. We show here
that viruses obtained from the Democratic Republic of Congo in Africa have a quantitatively …

Reconstruction and future trends of the AIDS epidemic in the United States

R Brookmeyer - Science, 1991 - science.org
There has been considerable uncertainty in estimates of past and current human
immunodeficiency virus (HIV) infection rates in the United States. Statistical estimates of …

Possible demographic consequences of AIDS in developing countries

RM Anderson, RM May, AR Mclean - Nature, 1988 - nature.com
Simple mathematical models of the transmission dynamics of HIV that incorporate
demographic and epidemiological processes to assess the potential impact of AIDS on …

How does HIV cause AIDS?

RA Weiss - Science, 1993 - science.org
Many questions have been posed about acquired immunodeficiency syndrome (AIDS)
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …

A highly virulent variant of HIV-1 circulating in the Netherlands

C Wymant, D Bezemer, F Blanquart, L Ferretti, A Gall… - Science, 2022 - science.org
We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred
nine individuals with this variant had a 0.54 to 0.74 log10 increase (ie, a~ 3.5-fold to 5.5-fold …

Timing the ancestor of the HIV-1 pandemic strains

B Korber, M Muldoon, J Theiler, F Gao, R Gupta… - science, 2000 - science.org
HIV-1 sequences were analyzed to estimate the timing of the ancestral sequence of the
main group of HIV-1, the strains responsible for the AIDS pandemic. Using parallel …

Comparative population dynamics of HIV-1 subtypes B and C: subtype-specific differences in patterns of epidemic growth

PR Walker, OG Pybus, A Rambaut… - Infection, Genetics and …, 2005 - Elsevier
The human immunodeficiency virus (HIV) pandemic continues to grow at an alarming rate,
with a further 5 million new infections in 2003. Some 3.5 million of these were in sub …