Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

In April 2014, the World Health Organization announced the beginning of a post-antibiotic
era and declared antimicrobial resistance (AMR) a public health priority demanding global …

Abstract 2017 marked the 30th anniversary of the approval of zidovudine (AZT) as the first
HIV/AIDS therapy. Since then, more than eighty antiviral drugs have received FDA approval …

Many antiviral drugs are currently approved and formally licensed for clinical use in the
treatment of viral infections caused by human immunodeficiency virus, herpes simplex …

This review highlights ten “hot topics” in current antiviral research:(i) new nucleoside
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …

Among the myriad infectious disease threats humans face from bacteria, prions, parasites,
protozoa, fungi, ectoparasites, and viruses, it is viral infections that arguably constitute the …

Antibiotic resistance is projected to be one of the greatest healthcare challenges of this
century. As the efficacy of these critical drugs wanes and discovery of new agents stagnates …

The current armamentarium for the chemotherapy of viral infections consists of 37 licensed
antiviral drugs. For the treatment of human immunodeficiency virus (HIV) infections, 19 …

Viruses are a serious threat for humans worldwide because there are in their ranks many
causative agents of potentially fatal infections and cancers [1, 2]. Despite this, emerging or re …

This article describes several approaches to a selective therapy of virus infections:(E)-5-(2-
bromovinyl)-2'-deoxyuridine (BVDU [brivudin]) for the therapy of herpes simplex virus type 1 …