Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome
AE Shikov, YA Barbitoff, AS Glotov, MM Danilova… - Frontiers in …, 2020 - frontiersin.org
Objectives In March 2020, the World Health Organization declared that an infectious
respiratory disease caused by a new severe acute respiratory syndrome coronavirus 2 …
respiratory disease caused by a new severe acute respiratory syndrome coronavirus 2 …
[HTML][HTML] Allelic and genotypic analysis of the ACE I/D polymorphism for the possible prediction of COVID-19-related mortality and morbidity in Jordanian Arabs
LN AL-Eitan, SZ Alahmad - Journal of Biosafety and Biosecurity, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread
worldwide, posing a global medical concern. This novel RNA virus enters cells by binding to …
worldwide, posing a global medical concern. This novel RNA virus enters cells by binding to …
Association of the ACE and AGT gene polymorphisms with global disparities in COVID-19-related deaths
YB Saab, ZS Nakad, SJ Mehanna - Pharmacogenetics and …, 2023 - journals.lww.com
Objective The aim of the study was to investigate the gene polymorphisms of angiotensin-
converting enzyme (ACE), angiotensinogen (AGT), and angiotensin type 1 receptor (AT1R) …
converting enzyme (ACE), angiotensinogen (AGT), and angiotensin type 1 receptor (AT1R) …
Clinical population genetic analysis of variants in the SARS-CoV-2 receptor ACE2
A Ardeshirdavani, P Zakeri, A Mehrtash, SM Hosseini… - medRxiv, 2020 - medrxiv.org
Purpose SARS-CoV-2 infects cells via the human Angiotensin-converting enzyme 2 (ACE2)
protein. The genetic variation of ACE2 function and expression across populations is still …
protein. The genetic variation of ACE2 function and expression across populations is still …
Investigation of polymorphisms of ACEII gene in people with coronavirus with severe and mild symptoms or asymptomatic
F Arab, M Jafari Rad, SA Esmaeili… - International Journal of …, 2022 - ijtmgh.com
Introduction: Angiotensin-converting enzyme 2 (ACE2) is the central receptor of coronavirus
disease 2019 (COVID-19) in host cells. Genetic polymorphisms in the ACE2 gene may …
disease 2019 (COVID-19) in host cells. Genetic polymorphisms in the ACE2 gene may …
SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease
COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …
Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease
M Sabater Molina, E Nicolás Rocamora, AI Bendicho… - PloS one, 2022 - journals.plos.org
Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis
N Pouladi, S Abdolahi - Molecular Genetics & Genomic …, 2021 - Wiley Online Library
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …
[HTML][HTML] The impact of ACE2 polymorphisms on COVID-19 disease: susceptibility, severity, and therapy
F Chen, Y Zhang, X Li, W Li, X Liu… - Frontiers in Cellular and …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has currently spread worldwide, leading to high morbidity and …
coronavirus 2 (SARS-CoV-2), has currently spread worldwide, leading to high morbidity and …
Genetic hypothesis and pharmacogenetics side of renin-angiotensin-system in COVID-19
The importance of host genetics and demography in coronavirus disease 2019 (COVID-19)
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …