The lung is a key target of the cytokine storm that can be triggered by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the widespread clinical …

Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

Among patients suffering from coronavirus disease 2019 (COVID-19) syndrome, one of the
worst possible scenarios is represented by the critical lung damage caused by the severe …

A severe pneumonia-associated respiratory syndrome caused by a new coronavirus was
identified in December 2019 (COVID-19), spread rapidly and has become a world-wide …

Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial …

Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. This …

The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome
(COVID-CSS) emerged early in the severe acute respiratory syndrome coronavirus 2 (SARS …

COVID-19, caused by the novel severe acute respiratory coronavirus 2 (SARS-CoV-2),
emerged in Wuhan, China, in 2019 and has resulted in the current pandemic. The disease …

The lung is the major target organ of SARS-CoV-2 infection, which causes COVID-19. Here,
we outline the multistep mechanisms of lung epithelial and endothelial injury induced by …

Background To date, specific cytokines associated with development of acute respiratory
distress syndrome (ARDS) and extrapulmonary multiple organ dysfunction (MOD) in COVID …