Cisplatin (CP) is a chemotherapy drug widely prescribed to treat various neoplasms.
Although fundamental for the therapeutic action of the drug, its cytotoxic mechanisms trigger …

Cisplatin is currently one of the most widely-used chemotherapeutic agents against various
malignancies. Its clinical application is limited, however, by inherent renal and cardiac …

Cisplatin (CP) was recognized as a proficient antineoplastic agent; which has an
indispensable role in facing various forms of malignancies such as breast, bladder, cervical …

Cisplatin is a highly effective antitumor agent whose clinical application is limited by the
inherent nephrotoxicity. The current measures of nephroprotection used in patients receiving …

Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Cisplatin is among the most effective chemotherapeutic agents against solid tumors.
Nephrotoxicity is the most common side effect of cisplatin chemotherapy, which limits the …

Cisplatin (cis-diamminedichloroplatinum II) is a widely used chemotherapeutic agent.
However, efficacy and clinical utility of this drug is significantly limited by severe side effects …

Nephrotoxicity represents one of the cutting-edge topics of our journal (Francescato et al.
2011; Stewart et al. 2011a, b; Faiz et al. 2011; Briguori et al. 2011; Song et al. 2011; Abdel …

Nephrotoxic drugs are responsible for approximately 20% of the episodes of acute kidney
injury (AKI) in hospital and outpatient settings. Among elderly individuals, the incidence of …

Cisplatin is one of the most widely used chemotherapeutic agents for the treatment of
several human malignancies. The efficacy of cisplatin is dose dependent, but the significant …