Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

SARS‐CoV‐2 infection‐induced immune responses: Friends or foes?

K Li, Z Hao, X Zhao, J Du, Y Zhou - Scandinavian Journal of …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is an emerging
coronavirus that belongs to the β‐genus, causing the outbreak of coronavirus disease 19 …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

SARS–CoV-2 immuno-pathogenesis and potential for diverse vaccines and therapies: opportunities and challenges

AR McGill, R Khalil, R Dutta, R Green, M Howell… - Infectious Disease …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel coronavirus
that emerged from Wuhan, China in late 2019 causing coronavirus disease-19 (COVID-19) …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

Hyperinflammation and immune response generation in COVID-19

KP Mishra, AK Singh, SB Singh - Neuroimmunomodulation, 2021 - karger.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that causes coronavirus
disease 2019 (COVID-19) pandemic has affected millions of people worldwide. The …

Innate immune response to SARS-CoV-2 infection: From cells to soluble mediators

D Ricci, MP Etna, F Rizzo, S Sandini, M Severa… - International journal of …, 2021 - mdpi.com
The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity,
the unpredictability of the infection outcome, and the high transmissibility, broad tissue …

Immunomodulation as a potent COVID-19 pharmacotherapy: Past, present and future

DM Hertanto, BS Wiratama, H Sutanto… - Journal of …, 2021 - Taylor & Francis
In the first year of its appearance, the 2019 coronavirus disease (COVID-19) has affected
more than 150 million individuals and killed 3 million people worldwide. The pandemic has …

Immunomodulation as treatment for severe coronavirus disease 2019: a systematic review of current modalities and future directions

EA Meyerowitz, P Sen, SR Schoenfeld… - Clinical Infectious …, 2021 - academic.oup.com
In severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, viral load
peaks early and declines quickly after symptom onset. Severe coronavirus disease 2019 …