Convalescent plasma: therapeutic hope or hopeless strategy in the SARS-CoV-2 pandemic

HC Sullivan, JD Roback - Transfusion medicine reviews, 2020 - Elsevier
As the world faces the current SARS-CoV-2 pandemic, extensive efforts have been applied
to identify effective therapeutic agents. Convalescent plasma collected from recovered …

[HTML][HTML] Treatment for emerging viruses: Convalescent plasma and COVID-19

BL Brown, J McCullough - Transfusion and Apheresis Science, 2020 - Elsevier
Use of convalescent plasma transfusions could be of great value in the current pandemic of
coronavirus disease (COVID-19), given the lack of specific preventative and therapeutic …

[HTML][HTML] The emerging role of convalescent plasma in the treatment of COVID-19

T Psaltopoulou, TN Sergentanis, V Pappa… - …, 2020 - journals.lww.com
Various agents are currently under evaluation as potential treatments in the fight against
coronavirus disease 2019 (COVID-19). Plasma from patients that have overcome COVID-19 …

[HTML][HTML] Deployment of convalescent plasma for the prevention and treatment of COVID-19

EM Bloch, S Shoham, A Casadevall… - The Journal of …, 2020 - Am Soc Clin Investig
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2), the cause of coronavirus
disease 2019 (COVID-19), has spurred a global health crisis. To date, there are no proven …

A randomized trial of convalescent plasma for COVID-19—potentially hopeful signals

A Casadevall, MJ Joyner, LA Pirofski - Jama, 2020 - jamanetwork.com
Convalescent plasma for the treatment of infectious diseases has been used since the early
20th century and was associated with reduced mortality during the 1918 influenza, 1 2003 …

[HTML][HTML] Pivotal role of convalescent plasma in managing emerging infectious diseases

HK Wong, CK Lee - Vox sanguinis, 2020 - ncbi.nlm.nih.gov
Infectious diseases remain one of the top 10 global health threats as announced by the
World Health Organization [1]. The emergence of new pathogens for which there is no …

[HTML][HTML] COVID-19 convalescent plasma: now is the time for better science

S Dzik - Transfusion medicine reviews, 2020 - ncbi.nlm.nih.gov
In this issue of Transfusion Medicine Reviews, we are pleased to offer readers an
assessment as of April 2020 of COVID-19 convalescent plasma (CCP) by H Cliff Sullivan …

[HTML][HTML] Treatment of COVID-19 with convalescent plasma: lessons from past coronavirus outbreaks

DJ Wooding, H Bach - Clinical Microbiology and Infection, 2020 - Elsevier
Background There is currently no treatment known to alter the course of coronavirus disease
2019 (COVID-19). Convalescent plasma has been used to treat a number of infections …

[HTML][HTML] Convalescent plasma to treat coronavirus disease 2019 (COVID‐19): considerations for clinical trial design

P Barone, RA DeSimone - Transfusion, 2020 - ncbi.nlm.nih.gov
• Previous studies of convalescent plasma in treating other viral diseases have identified
factors to consider when designing treatment protocols, including timing of administration …

Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion

X Xia, K Li, L Wu, Z Wang, M Zhu… - Blood, The Journal …, 2020 - ashpublications.org
Two case series examining the impact of convalescent plasma on patients with COVID-19
suggest some clinical benefit from early administration and modest impact on parameters of …