Purpose Constitutional WT1 mutations in patients with Wilms' tumor (WT) have specifically
been associated with genitourinary abnormalities, such as cryptorchidism and hypospadias …

PURPOSE Patients with Wilms' tumors (WT) who carry constitutional mutations in the WT1
gene have been described in case reports and small case series. We sought to determine …

We report here 24 new Wilms tumor (WT) patients with germline WT1 alterations and a
synopsis of our own previously described and literature cases in whom age of tumor‐onset …

Study of genotype/phenotype relationships involving the Wilms' tumor (WT) gene, WT1, in
WT patients has provided insights into the function of the WT1 protein, a transcriptional …

INTRODUCTION: In 9–17% of Wilms tumour patients a predisposing syndrome is present, in
particular WT1-associated syndromes and overgrowth syndromes. Constitutional WT1 …

Background: Bilateral Wilms tumours (BWTs) occur by germline mutation of various
predisposing genes; one of which is WT1 whose abnormality was reported in 17–38% of …

Mutations in the WT1 gene causing Wilms tumors were first reported in WAGR syndrome
(Wilms tumor, Aniridia, Genitourinary malformation, mental Retardation) and Denys Drash …

To the Editor: Wilms tumor (WT), the most frequent pediatric renal tumor, primarily occurs as
a sporadic disease, but approximately 2% of cases have an affected relative [1]. While the …

Abstract Wilms' tumor (WT), the most common childhood kidney cancer, develops in
association with an underlying germline predisposition in up to 15% of cases. Germline …

Purpose Children's Oncology Group defines very low-risk Wilms tumors (VLRWT) as stage I
favorable histology Wilms tumors weighing less than 550 g in children younger than 24 …