Cytokine storm in COVID‐19 patients, its impact on organs and potential treatment by QTY code‐designed detergent‐free chemokine receptors

MI Mustafa, AH Abdelmoneim… - Mediators of …, 2020 - Wiley Online Library
The novel coronavirus is not only causing respiratory problems, but it may also damage the
heart, kidneys, liver, and other organs; in Wuhan, 14 to 30% of COVID‐19 patients have lost …

[HTML][HTML] Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 9.2 million …

[HTML][HTML] Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic …

[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
SARS-Cov-2 infection causes local and systemic inflammation mediated by pro-
inflammatory cytokines and COX-2 eicosanoid products with metabolic dysfunction and …

[HTML][HTML] Targeting macrophages as a therapeutic option in coronavirus disease 2019

M Gracia-Hernandez, EM Sotomayor… - Frontiers in …, 2020 - frontiersin.org
Immune cells of the monocyte/macrophage lineage are characterized by their diversity,
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …

[HTML][HTML] An engineered nano-liposome-human ACE2 decoy neutralizes SARS-CoV-2 Spike protein-induced inflammation in both murine and human macrophages

S Satta, Z Meng, R Hernandez, S Cavallero, T Zhou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Macrophages are the frontline immune cells in response to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Angiotensin-converting …

Capturing cytokines with advanced materials: a potential strategy to tackle COVID‐19 cytokine storm

QF Meng, R Tian, H Long, X Wu, J Lai… - Advanced …, 2021 - Wiley Online Library
The COVID‐19 pandemic, induced by severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2), has caused great impact on the global economy and people's daily life. In …