A large amount of evidence suggests a pathogenic link between cholesterol homeostasis
dysregulation and Alzheimer's disease (AD). In cell culture systems, the production of …

During the last 2 decades, evidence has accumulated that a high cholesterol level may
increase the risk of developing Alzheimer disease (AD). With the global use of statins to treat …

The implication that cholesterol plays an essential role in the pathogenesis of Alzheimer's
disease (AD) is based on the 1993 finding that the presence of apolipoprotein E (apoE) …

The link between cholesterol and Alzheimer's disease (AD) is indicated by genetic,
epidemiological, experimental and clinical evidence, although the relationship is far from …

Statins have been used for many years for the treatment of hypercholesterolemia. They
lower low-density lipoprotein (LDL) cholesterol, increase high-density lipoprotein (HDL) …

A link between alterations in cholesterol homeostasis and Alzheimer's disease (AD) is
nowadays widely accepted. However, the molecular mechanism/s underlying such link …

Experimental in vitro and in vivo findings as well as some retrospective epidemiological
studies link cholesterol homeostasis with Alzheimer''s disease (AD), and there are some …

Evidences from cell culture experiments and animal studies suggest a strong link between
cholesterol and Alzheimer's disease (AD). This relationship is supported by retrospective …

Disease-modifying therapies are being developed for Alzheimer's disease (AD). These are
expected to slow the clinical progression of the disease or delay its onset. Cerebral …

Alzheimer's disease (AD) is the principal cause of dementia in older people, and
accumulation of amyloid-beta (Aβ) peptide is a crucial event in AD pathogenesis. Despite …