[HTML][HTML] IL1β, IL-6, and TNF-α cytokines cooperate to modulate a complicated medical condition among COVID-19 patients: case-control study

SS Faraj, PJ Jalal - Annals of Medicine and Surgery, 2023 - journals.lww.com
Background: The cytokine storm is a complication related to SARS-CoV-2 infection
worldwide. This study aimed to address the level of three cytokines which were interleukin-1 …

Elevated levels of pleiotropic interleukin-6 (IL-6) and interleukin-10 (IL-10) are critically involved with the severity and mortality of COVID-19: An updated longitudinal …

S Jafrin, MA Aziz, MS Islam - Biomarker Insights, 2022 - journals.sagepub.com
Objectives: Disruption in the natural immune reaction due to SARS-CoV-2 infection can
initiate a potent cytokine storm among COVID-19 patients. An elevated level of IL-6 and IL …

[HTML][HTML] Differences of blood cells, lymphocyte subsets and cytokines in COVID-19 patients with different clinical stages: a network meta-analysis

W Yan, D Chen, FM Bigambo, H Wei, X Wang… - BMC infectious …, 2021 - Springer
Background Due to the rapid spread of coronavirus disease 2019 (COVID-19) worldwide, it
is necessary to ascertain essential immune inflammatory parameters that describe the …

Downregulated gene expression spectrum and immune responses changed during the disease progression in patients with COVID-19

Y Ouyang, J Yin, W Wang, H Shi, Y Shi… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background The World Health Organization characterizes novel coronavirus
disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome …

[HTML][HTML] The inflammatory biomarkers profile of hospitalized patients with COVID-19 and its association with patient's outcome: A single centered study

IY Hachim, MY Hachim, H Hannawi, KB Naeem… - PLoS …, 2021 - journals.plos.org
Several reports highlighted the central role of inflammation in the pathogenesis of corona
virus disease-19 (COVID-19) disease. Also, the hyper-inflammatory response that is …

[HTML][HTML] Factors of severity in patients with COVID-19: cytokine/chemokine concentrations, viral load, and antibody responses

JS Kwon, JY Kim, MC Kim, SY Park… - The American journal …, 2020 - ncbi.nlm.nih.gov
The severity of COVID-19 ranges from mild to critical diseases. However, limited data have
been published on the detailed kinetics of viral load and host immune response throughout …

Predicting disease severity and outcome in COVID-19 patients: a review of multiple biomarkers

Y Tjendra, AF Al Mana, AP Espejo… - … of pathology & …, 2020 - meridian.allenpress.com
Context.—An abundance of clinical reports focused on specific laboratory parameters have
been reported on coronavirus disease 19 (COVID-19), but a systematic analysis …

[HTML][HTML] Pattern of inflammatory immune response determines the clinical course and outcome of COVID-19: unbiased clustering analysis

EE Lee, KH Song, W Hwang, SY Ham, H Jeong… - Scientific reports, 2021 - nature.com
The objective of the study was to identify distinct patterns in inflammatory immune responses
of COVID-19 patients and to investigate their association with clinical course and outcome …

[HTML][HTML] IL-6 and CD8+ T cell counts combined are an early predictor of in-hospital mortality of patients with COVID-19

M Luo, J Liu, W Jiang, S Yue, H Liu, S Wei - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Fatal cases of COVID-19 are increasing globally. We retrospectively
investigated the potential of immunologic parameters as early predictors of COVID-19 …

Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19

H Satış, HS Özger, PA Yıldız, K Hızel, Ö Gulbahar… - Cytokine, 2021 - Elsevier
Background The effectual immune response is crucial to defeat viral infections. However,
exuberant immune response with features of macrophage activation syndrome (MAS) lead …