Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …

SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from
silent infection to lethal disease. The role of human genetics in determining clinical response …

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

Background Susceptibility to severe viral infections was reported to be associated with
genetic variants in immune response genes using case reports and GWAS studies. SARS …

The host response to SARS-CoV-2, the etiologic agent of the COVID-19 pandemic,
demonstrates significant interindividual variability. In addition to showing more disease in …

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between
individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive …

The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …