[HTML][HTML] Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children

U Nygaard, AB Nielsen, KHS Dungu, L Drici… - Communications …, 2024 - nature.com
Multisystem inflammatory syndrome in children (MIS-C) is a severe disease that emerged
during the COVID-19 pandemic. Although recognized as an immune-mediated condition …

[HTML][HTML] The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children

RA Porritt, A Binek, L Paschold… - The Journal of …, 2021 - Am Soc Clin Investig
Multisystem inflammatory syndrome in children (MIS-C) manifests as a severe and
uncontrolled inflammatory response with multiorgan involvement, occurring weeks after …

Proteomic profiling of MIS-C patients reveals heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction

C Diorio, R Shraim, LA Vella, JR Giles, AE Baxter… - medRxiv, 2021 - medrxiv.org
Abstract Multi-system Inflammatory Syndrome in Children (MIS-C) is a major complication of
the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic in …

[HTML][HTML] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …

[HTML][HTML] Distinct phenotypes of multisystem inflammatory syndrome in children: a cohort study

T Renson, ND Forkert, K Amador, P Miettunen… - Pediatric …, 2023 - Springer
Background Multisystem inflammatory syndrome in children (MIS-C) is a severe disease
with an unpredictable course and a substantial risk of cardiogenic shock. Our objectives …

[HTML][HTML] MIS-C: early lessons from immune profiling

LA Henderson, RSM Yeung - Nature Reviews Rheumatology, 2021 - nature.com
Multisystem inflammatory syndrome in children (MIS-C) is a rare complication of SARS-CoV-
2 infection that can result in serious illness in the paediatric population but our …

Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity

A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - medRxiv, 2020 - medrxiv.org
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV2 …

Multisystem inflammatory syndrome in children (MIS-C) temporally associated with SARS-CoV-2 infection: a scoping review of the literature

M Sabbour, ST El-Swaify, N Farrag, M Kamel, SH Ali… - medRxiv, 2020 - medrxiv.org
Background With the rise of the COVID-19 pandemic, a new severe life-threatening
inflammatory syndrome has been reported in some pediatric populations. Global attention …

[HTML][HTML] Case report: Immune profiling links neutrophil and plasmablast dysregulation to microvascular damage in post-COVID-19 Multisystem Inflammatory Syndrome …

MR Gillrie, N Rosin, S Sinha, H Kang, R Farias… - Frontiers in …, 2023 - frontiersin.org
Despite surviving a SARS-CoV-2 infection, some individuals experience an intense post-
infectious Multisystem Inflammatory Syndrome (MIS) of uncertain etiology. Children with this …

[HTML][HTML] Multisystem inflammatory syndrome in children: a systematic review

M Ahmed, S Advani, A Moreira, S Zoretic… - …, 2020 - thelancet.com
Background Multisystem inflammatory syndrome in children (MIS-C), also known as
pediatric inflammatory multisystem syndrome, is a new dangerous childhood disease that is …